Breaking the stromal barrier in pancreatic cancer: Advances and challenges
M Chakkera, JB Foote, B Farran… - Biochimica et Biophysica …, 2023 - Elsevier
Pancreatic cancer (PC) remains a leading cause of mortality worldwide due to the absence
of early detection methods and the low success rates of traditional therapeutic strategies …
of early detection methods and the low success rates of traditional therapeutic strategies …
HGF/c-MET: A Potential Target for the Treatment of Various Cancers
Background: Cancer is the abnormal growth of cells in the body due to an imbalance in the
normal apoptotic pathways. The abnormality in the cancer cells makes them malignant …
normal apoptotic pathways. The abnormality in the cancer cells makes them malignant …
[HTML][HTML] Current trends and research hotspots in pancreatic stellate cells: A bibliometric study
Z Yang, Z Xie, J Wan, B Yi, T Xu, X Shu, Z Zhao… - Frontiers in …, 2022 - frontiersin.org
Background Pancreatic stellate cells (PSCs) play crucial roles in acute/chronic pancreatitis
and pancreatic cancer. In this study, bibliometric analysis was used to quantitatively and …
and pancreatic cancer. In this study, bibliometric analysis was used to quantitatively and …
Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library
M Mortazavi, E Raufi, T Damghani… - European journal of …, 2023 - Elsevier
Abstract c-Met receptor tyrosine kinase has recently emerged as an important target with
therapeutic implications in pancreatic cancer. In this study, we carried out a docking virtual …
therapeutic implications in pancreatic cancer. In this study, we carried out a docking virtual …
[HTML][HTML] Advancement of single-cell sequencing for clinical diagnosis and treatment of pancreatic cancer
K Zhang, Y Chen, J Zhu, X Ge, J Wu, P Xu… - Frontiers in Medicine, 2023 - frontiersin.org
Single-cell sequencing is a high-throughput technique that enables detection of genomic,
transcriptomic, and epigenomic information at the individual cell level, offering significant …
transcriptomic, and epigenomic information at the individual cell level, offering significant …
A journey to and with the stars: The pancreatic stellate cell story
M Apte - Pancreatology, 2023 - Elsevier
Abstract The George E Palade Prize is the highest honour awarded by the International
Association of Pancreatology, that recognises an individual who has made outstanding …
Association of Pancreatology, that recognises an individual who has made outstanding …
Tumor Microenvironment: Immune Cells and Immunosuppressive Functions of Carcinoma‐associated Fibroblasts and Macrophages
Pancreatic ductal adenocarcinoma (PDAC), one of the most devastating cancers of our time,
has a dismal prognosis. PDAC is characterized by a prominent desmoplastic reaction and …
has a dismal prognosis. PDAC is characterized by a prominent desmoplastic reaction and …