Chronic obstructive pulmonary disease (COPD) is a deadly and highly morbid disease.
Susceptibility to and heterogeneity of COPD are incompletely explained by environmental …

Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …

Polygenic risk scores (PRSs) are weighted sums of risk allele counts of single‐nucleotide
polymorphisms (SNPs) associated with a disease or trait. PRSs are typically constructed …

COPD, characterized by long-term poorly irreversible airway limitation and persistent
respiratory symptoms, has resulted in enormous challenges to human health worldwide …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of lung diseases
limiting the airflow due to narrowing of airways, chronic bronchitis and emphysema that …

The landmark, multicenter HCHS/SOL (Hispanic Community Health Study/Study of Latinos)
is the largest, most comprehensive, longitudinal community-based cohort study to date of …

Chronic obstructive pulmonary disease (COPD), diagnosed by reduced lung function, is a
leading cause of morbidity and mortality. We performed whole genome sequence (WGS) …

Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of
European ancestry populations. We extend previous research by meta-analyzing genome …

Background Few low-middle-income countries have data from comparable birth cohort
studies spanning over time. We report on the methods used by the Pelotas cohorts (1982 …

In the US, the burden of asthma and COPD varies across racial or ethnic groups, largely
because of unequal exposure to environmental exposures such as tobacco smoke and …