Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an
essential role in the maintenance of cell integrity and protection against DNA damage by …

Epigenetic silencing of gluthathione‐S‐transferase pi (GSTP1) is recognized as being a
molecular hallmark of human prostate cancer. We investigated the effects of green tea …

Prostate cancer (PCa) incidence and mortality have decreased in recent years.
Nonetheless, it remains one of the most prevalent cancers in men, being a disquieting cause …

DNA hypermethylation is a common epigenetic alteration in human prostate cancer and is
considered to contribute to development of this disease. Accumulating data suggest that …

Background Accumulating evidence indicates that in utero exposure to arsenic is associated
with congenital defects and long-term disease consequences including cancers. Recent …

The aim of this study was to investigate the effects of plant phenolic compound tannic acid
(TA) on proliferative, metastatic, invasive properties of prostate cancer (PCa) cells; PC-3 and …

Abstract Background Multidrug resistance 1 (MDR1) gene encodes for an ATP binding
cassette transporter-P-glycoprotein (P-gp)-involved in chemoresistance to taxanes. MDR1 …

Na+/I− symporter (NIS)-mediated radioiodide uptake (RAIU) serves as the basis for targeted
ablation of thyroid cancer remnants. However, many patients with thyroid cancer have …

The aryl hydrocarbon receptor (AhR) is a ligand-activated regulatory protein that controls
estrogen action through two distinct pathways. In one pathway, AhR acts as a transcription …

It is now well established that cancer cells exhibit a number of genetic defects in the
machinery that governs programmed cell death and that sabotage of apoptosis is one of the …