Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Psoriasis is a systemic, chronic, immune-mediated disease that affects approximately 2–3%
of the world's population. The etiology and pathophysiology of psoriasis are still unknown …

The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic
inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis …

Abstract The IL-23/IL-17 cytokine axis is related to spondyloarthropathy (SpA) pattern
diseases that target the skin, eye, gut and joints. These share overlapping target tissues with …

Atopic dermatitis and psoriasis are two of the most common chronic skin conditions. Current
target therapies represent viable and safe solutions for the most severe cases of these two …

Background Psoriasis is a chronic inflammatory dermatosis with an unclear pathogenesis.
Mast cells (MCs) can serve as a bridge between innate and adaptive immunity and are …

Preeclampsia (PE), a leading cause of maternal/fetal morbidity and mortality, is a
hypertensive pregnancy disorder with end-organ damage that manifests after 20 wk of …

Introduction: IL-1 family cytokines play an important role in the innate immune system and
their uncontrolled activation and expression can initiate a pathologic inflammatory response …

Skin epidermis constitutes the exterior barrier that protects the body from dehydration and
environmental assaults. Barrier defects underlie common inflammatory skin diseases, but …

Preeclampsia (PE) is a pregnancy-specific hypertensive disorder with end-organ damage
that presents after 20 wk of gestation. PE pathophysiology often includes vascular …