The CONSORT 2010 statement provides minimum guidelines for reporting randomised
trials. Its widespread use has been instrumental in ensuring transparency in the evaluation …

Objective Although the role of artificial intelligence (AI) in medicine is increasingly studied,
most patients do not benefit because the majority of AI models remain in the testing and …

This chapter describes the principles and methods used to carry out a meta‐analysis for a
comparison of two interventions for the main types of data encountered. A very common and …

The term “real-world evidence” is widely used by those who develop medical products or
who study, deliver, or pay for health care, but its specific meaning is elusive. We believe it …

Untitled Page 1 Page 2 REALIST RESEARCH DOING Page 3 Sara Miller McCune founded
SAGE Publishing in 1965 to support the dissemination of usable knowledge and educate a …

There is currently much debate about the effectiveness of foreign aid and about what kind of
projects can engender economic development. There is skepticism about the ability of …

We consider the problem of identifying a subgroup of patients who may have an enhanced
treatment effect in a randomized clinical trial, and it is desirable that the subgroup be defined …

The explanation and implementation of statistical methods for the medical researcher or
statistician remains an integral part of modern medical research. This book explains the use …

Context Recent reports highlight gaps between guidelines-based treatment
recommendations and evidence from clinical trials that supports those recommendations …

This chapter aims to support review authors who are considering including non‐randomized
studies of interventions (NRSI) in a Cochrane Review. NRSI are defined here as any …