Sensory nerves and airway irritability

BJ Canning, D Spina - Sensory Nerves, 2009 - Springer
The lung, like many other organs, is innervated by a variety of sensory nerves and by nerves
of the parasympathetic and sympathetic nervous systems that regulate the function of cells …

Effects of in-vitro modulation of TRPV1 activity on immune response of mice bearing metastatic breast carcinoma: Enhanced inflammatory response may hinder …

N Erin, M Akman - Life Sciences, 2021 - Elsevier
Aims Activation of transient receptor potential vanilloid 1 (TRPV1) ion channels inhibits
inflammation, enhance cytotoxic immune response, and may have therapeutic potential in …

Senso‐immunology: crosstalk between nociceptive and immune systems

K Maruyama - The FEBS journal, 2022 - Wiley Online Library
Understanding the molecular mechanisms of nociception has recently grown impressively.
Nociception is mediated by mechanical, chemical, or microbial stimuli that evoke unpleasant …

[HTML][HTML] The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in …

Z Bromberg, P Goloubinoff, Y Saidi, YG Weiss - PloS one, 2013 - journals.plos.org
The heat shock response (HSR) is a highly conserved molecular response to various types
of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to …

Transient receptor potential ion channels: powerful regulators of cell function

AT Billeter, JL Hellmann, A Bhatnagar… - Annals of surgery, 2014 - journals.lww.com
Objective: This article reviews the current understanding of transient receptor potential ion
channels (TRP channels) in health and disease. Background: Transient receptor potential …

Inhibition of the function of TRPV1-expressing nociceptive sensory neurons by somatostatin 4 receptor agonism: echanism and therapeutical Implications

J Szolcsanyi, E Pinter, Z Helyes… - Current topics in …, 2011 - ingentaconnect.com
Release of somatostatin into the circulation from the activated TRPV1-expressing
nociceptors revealed by antidromic stimulation of dorsal roots in the rat pinpointed to a novel …

TRPV1 ablation aggravates inflammatory responses and organ damage during endotoxic shock

Y Wang, DH Wang - Clinical and Vaccine Immunology, 2013 - Am Soc Microbiol
To test the hypothesis that ablation of transient receptor potential vanilloid type 1 (TRPV1)
channels leads to exacerbated inflammatory responses and organ damage during …

4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and-independent nociceptive and vasoactive responses in vivo

R Graepel, ES Fernandes, AA Aubdool… - … of Pharmacology and …, 2011 - ASPET
This study explores the in vivo effects of the proposed transient receptor potential ankyrin 1
(TRPA1) agonist 4-oxo-2-nonenal (4-ONE). Pharmacological inhibitors and genetically …

[HTML][HTML] Lipopolysaccharide pretreatment increases the sensitivity of the TRPV1 channel and promotes an anti-inflammatory phenotype of capsaicin-activated …

D Vašek, N Fikarová, VN Marková, O Honc… - Journal of …, 2024 - Springer
Background The transient receptor potential vanilloid 1 (TRPV1) is well-established in
neuronal function, yet its role in immune reactions remains enigmatic. The conflicting data …

[HTML][HTML] Cross-talk between neural and immune receptors provides a potential mechanism of homeostatic regulation in the gut mucosa

BM Assas, JA Miyan, JL Pennock - Mucosal immunology, 2014 - Elsevier
The relationship between elements of the immune system and the nervous system in the
presence of bacteria has been addressed recently. In particular, the sensory vanilloid …