The gabapentinoids, gabapentin, and pregabalin, target the α2δ subunits of voltage-gated
calcium channels. Initially licensed for pain and seizures, they have become widely …

Rett syndrome is a rare, genetic neurodevelopmental disorder. Trofinetide is a synthetic
analog of glycine–proline–glutamate, the N-terminal tripeptide of the insulin-like growth …

Background Mental health outcome measures are used to monitor the quality and
effectiveness of mental health services. There is also a growing expectation for …

Importance Transdiagnostic interventions have been developed to address barriers to the
dissemination of evidence-based psychological treatments, but only a few preliminary …

Introduction Rett syndrome (RTT) is a debilitating neurodevelopmental disorder with no
approved treatments. Trofinetide is a synthetic analog of glycine–proline–glutamate, the N …

BACKGROUND: Accumulating evidence suggests an association between autism spectrum
disorders (ASD) and inflammation in brain regions related to cognitive function. The natural …

Abstract The Brief Psychiatric Rating Scale (BPRS) was originally conceived to assess
psychopathology in several psychiatric disorders, making it an appropriate candidate to be …

Objective: Irritability in disruptive mood dysregulation disorder (DMDD) may be associated
with a biased tendency to judge ambiguous facial expressions as angry. We conducted …

We tested whether augmenting conventional depression treatment in youth by treating sleep
issues with cognitive behavioral therapy for insomnia (CBT-I) improved depression …

Given the limited treatment options for trichotillomania (TTM), or Hair Pulling Disorder, this
large randomized clinical trial evaluated the efficacy of acceptance-enhanced behavior …