Estrogen receptor-positive (ER+) breast cancer is the most common breast cancer subtype.
Treatment of ER+ breast cancer comprises interventions that suppress estrogen production …

Abstract Coronavirus disease 2019 (COVID-19) has shown high infection and mortality rates
all over the world, and despite the global efforts, there is so far no specific therapy available …

The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Women have stronger immune responses to infections and vaccination than men.
Paradoxically, the stronger immune response comes at a steep price, which is the high …

Small-molecule drug discovery has traditionally focused on occupancy of a binding site that
directly affects protein function, and this approach typically precludes targeting proteins that …

Estrogen receptor alpha (ERα) is a well-established therapeutic target for the treatment of
ER-positive (ER+) breast cancers. Despite the tremendous successes achieved with …

Phytoestrogens are plant‐derived dietary compounds with structural similarity to 17‐β‐
oestradiol (E2), the primary female sex hormone. This structural similarity to E2 enables …

BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …