Cardiovascular disease is the most common health problem worldwide and remains the
leading cause of morbidity and mortality. Despite recent advances in the management of …

Although tremendous progress has been made in conventional treatment for ischemic heart
disease, it still remains a major cause of death and disability. Cell-based therapeutics holds …

Aims A better understanding of the pathways that regulate regeneration of the coronary
vasculature is of fundamental importance for the advancement of strategies to treat patients …

Despite advances in the treatment of acute myocardial infarction, due to the non-proliferative
nature of adult cardiomyocytes, the injured myocardium is mainly replaced by fibrotic tissue …

The regenerative capacity of an adult cardiac tissue is insufficient to repair the massive loss
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …

Heart disease remains a leading killer in western society and irreversibly impacts the lives of
millions of patients annually. While adult mammals do not possess the ability to regenerate …

Myocardial infarction (MI) remains a major cause of mortality worldwide. Despite significant
advances in MI treatment, many who survive the acute event are at high risk of chronic …

Introduction Myocardial infarction (MI) is an ischemic life-threatening disease with
exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane …

Ischemia-reperfusion injury (I/RI), produced by an initial interruption of organ blood flow and
its subsequent restoration, contributes significantly to the pathophysiologies of stroke …

Cardiovascular diseases (CVDs) are one of the most important causes of mortality and
affecting the health status of patients. At the same time, CVDs cause a huge health and …