Nanoparticle-based drug delivery systems for the treatment of cardiovascular diseases
F Yang, J Xue, G Wang, Q Diao - Frontiers in pharmacology, 2022 - frontiersin.org
Cardiovascular disease is the most common health problem worldwide and remains the
leading cause of morbidity and mortality. Despite recent advances in the management of …
leading cause of morbidity and mortality. Despite recent advances in the management of …
[HTML][HTML] Mesenchymal stem cell (MSCs) therapy for ischemic heart disease: a promising frontier
MS Poomani, I Mariappan, R Perumal, R Regurajan… - Global Heart, 2022 - ncbi.nlm.nih.gov
Although tremendous progress has been made in conventional treatment for ischemic heart
disease, it still remains a major cause of death and disability. Cell-based therapeutics holds …
disease, it still remains a major cause of death and disability. Cell-based therapeutics holds …
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
Aims A better understanding of the pathways that regulate regeneration of the coronary
vasculature is of fundamental importance for the advancement of strategies to treat patients …
vasculature is of fundamental importance for the advancement of strategies to treat patients …
Effectiveness of exosome mediated miR-126 and miR-146a delivery on cardiac tissue regeneration
Despite advances in the treatment of acute myocardial infarction, due to the non-proliferative
nature of adult cardiomyocytes, the injured myocardium is mainly replaced by fibrotic tissue …
nature of adult cardiomyocytes, the injured myocardium is mainly replaced by fibrotic tissue …
Nanoparticle-mediated drug delivery for treatment of ischemic heart disease
The regenerative capacity of an adult cardiac tissue is insufficient to repair the massive loss
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …
Decellularized neonatal cardiac extracellular matrix prevents widespread ventricular remodeling in adult mammals after myocardial infarction
Z Wang, DW Long, Y Huang, WCW Chen, K Kim… - Acta biomaterialia, 2019 - Elsevier
Heart disease remains a leading killer in western society and irreversibly impacts the lives of
millions of patients annually. While adult mammals do not possess the ability to regenerate …
millions of patients annually. While adult mammals do not possess the ability to regenerate …
MiR-101a loaded extracellular nanovesicles as bioactive carriers for cardiac repair
J Wang, CJ Lee, MB Deci, N Jasiewicz, A Verma… - … , Biology and Medicine, 2020 - Elsevier
Myocardial infarction (MI) remains a major cause of mortality worldwide. Despite significant
advances in MI treatment, many who survive the acute event are at high risk of chronic …
advances in MI treatment, many who survive the acute event are at high risk of chronic …
Thymoquinone protects against cardiac mitochondrial DNA loss, oxidative stress, inflammation and apoptosis in isoproterenol-induced myocardial infarction in rats
AA Khalifa, RM Rashad, WF El-Hadidy - Heliyon, 2021 - cell.com
Introduction Myocardial infarction (MI) is an ischemic life-threatening disease with
exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane …
exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane …
[HTML][HTML] Potential therapeutic roles of stem cells in ischemia-reperfusion injury
Ischemia-reperfusion injury (I/RI), produced by an initial interruption of organ blood flow and
its subsequent restoration, contributes significantly to the pathophysiologies of stroke …
its subsequent restoration, contributes significantly to the pathophysiologies of stroke …
Nanotechnology, an alternative with promising prospects and advantages for the treatment of cardiovascular diseases
T Li, W Liang, X Xiao, Y Qian - International journal of …, 2018 - Taylor & Francis
Cardiovascular diseases (CVDs) are one of the most important causes of mortality and
affecting the health status of patients. At the same time, CVDs cause a huge health and …
affecting the health status of patients. At the same time, CVDs cause a huge health and …