Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats

MM Khattab, MN Nagi - Phytotherapy Research: An …, 2007 - Wiley Online Library
The present study was undertaken to evaluate the protective effect of thymoquinone (TQ),
the main constituent of the volatile oil from Nigella sativa seeds, in rats after chronic …

Arbutus unedo prevents cardiovascular and morphological alterations in L-NAME-induced hypertensive rats: Part I: Cardiovascular and renal hemodynamic effects of …

S Afkir, TB Nguelefack, M Aziz, J Zoheir… - Journal of …, 2008 - Elsevier
Hypertension induced by nitric oxide synthase inhibition is associated with functional
abnormalities of the heart and kidney. The aim of the present study was to investigate …

Antihypertensive and cardioprotective effects of pumpkin seed oil

AEMK El-Mosallamy, AA Sleem… - Journal of Medicinal …, 2012 - liebertpub.com
Pumpkin seed oil is a natural product commonly used in folk medicine for treatment of
prostatic hypertrophy. In the present study, the effects of treatment with pumpkin seed oil on …

Acupuncture reduces experimental renovascular hypertension through mechanisms involving nitric oxide synthases

DD Kim, AM Pica, RG Durán, WN Durán - Microcirculation, 2006 - Taylor & Francis
Objective: To test the hypothesis that acupuncture on stomach 36 point (ST-36) reduces
hypertension by activating nitric oxide synthase signaling mechanisms. Methods: The …

Catecholamine-induced myocardial fibrosis and oxidative stress is attenuated by Terminalia arjuna (Roxb.)

S Kumar, R Enjamoori, A Jaiswal, R Ray… - Journal of pharmacy …, 2009 - academic.oup.com
Objectives Myocardial fibrosis and oxidative stress accompany a number of cardiac
disorders such as hypertrophic cardiomyopathy, hypertensive heart disease and cardiac …

[HTML][HTML] Antioxidant effects of captopril against lead acetate-induced hepatic and splenic tissue toxicity in Swiss albino mice

BA Aldahmash, DM El-Nagar - Saudi journal of biological sciences, 2016 - Elsevier
Considering that lead caused a lot of health problems in the world, the present study was
carried out to investigate the protective effect of captopril as antioxidants to reduce liver and …

Renoprotective effect of sitagliptin against hypertensive nephropathy induced by chronic administration of L-NAME in rats: role of GLP-1 and GLP-1 receptor

DM Abd El Motteleb, SM Elshazly - European journal of pharmacology, 2013 - Elsevier
The present study was undertaken to assess the possible protective effects of sitagliptin, a
dipeptidyl peptidase 4-inhibitor (DPP4), against Nω-nitro-L-arginine methyl ester (L-NAME) …

Antihypertensive Effects of the Vitex cienkowskii (Verbenaceae) Stem‐Bark Extract on L‐NAME‐Induced Hypertensive Rats

MF Metchi Donfack, AD Atsamo… - Evidence‐Based …, 2021 - Wiley Online Library
Vitex cienkowskii stem‐bark is used in Cameroonian traditional medicine to treat
cardiovascular diseases including hypertension. In previous studies, the …

[HTML][HTML] Effect of spironolactone and captopril on nitric oxide and S-nitrosothiol formation in kidney of L-NAME-treated rats

O Pechanova, J Matuskova, D Capikova… - Kidney international, 2006 - Elsevier
Although angiotensin-converting enzyme (ACE) inhibitors are well-established drugs in the
treatment of hypertension, they are not supposed to be sufficient in the inhibition of …

Lisinopril attenuates renal oxidative injury in l-NAME-induced hypertensive rats

F Öktem, A Kirbas, A Armagan, AE Kuybulu… - Molecular and cellular …, 2011 - Springer
Hypertension and related oxidative stress are involved in the pathogenesis of any renal
diseases. Angiotensin-converting enzyme inhibitors have multi-directional renoprotective …