[HTML][HTML] Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Blood-derived biomarkers for brain and spinal cord diseases are urgently needed. The
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
The impact of the gut microbiome on extra-intestinal autoimmune diseases
E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS
C Walton, R King, L Rechtman, W Kaye… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: High-quality epidemiologic data worldwide are needed to improve our
understanding of disease risk, support health policy to meet the diverse needs of people …
understanding of disease risk, support health policy to meet the diverse needs of people …
[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
[HTML][HTML] Systematic review and meta-analysis of the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)
EJ Lim, YC Ahn, ES Jang, SW Lee, SH Lee… - Journal of translational …, 2020 - Springer
Background Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) has been
emerging as a significant health issue worldwide. This study aimed to systemically assess …
emerging as a significant health issue worldwide. This study aimed to systemically assess …
[HTML][HTML] Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Background Neurological disorders are increasingly recognised as major causes of death
and disability worldwide. The aim of this analysis from the Global Burden of Diseases …
and disability worldwide. The aim of this analysis from the Global Burden of Diseases …
[HTML][HTML] Prevalence and burden of multiple sclerosis-related fatigue: a systematic literature review
A Oliva Ramirez, A Keenan, O Kalau, E Worthington… - BMC neurology, 2021 - Springer
Background Multiple sclerosis (MS) is a chronic, demyelinating disease of the central
nervous system that results in progressive and irreversible disability. Fatigue is one of the …
nervous system that results in progressive and irreversible disability. Fatigue is one of the …
[HTML][HTML] Thinking outside the box: non-canonical targets in multiple sclerosis
L Bierhansl, HP Hartung, O Aktas, T Ruck… - Nature reviews Drug …, 2022 - nature.com
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …
Racial and ethnic disparities in multiple sclerosis prevalence
AM Langer-Gould, EG Gonzales, JB Smith, BH Li… - Neurology, 2022 - AAN Enterprises
Background and Objectives The goal of this work was to determine whether the prevalence
of multiple sclerosis (MS) varies by race and ethnicity. Methods We conducted a …
of multiple sclerosis (MS) varies by race and ethnicity. Methods We conducted a …
[HTML][HTML] Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease
S Werneburg, J Jung, RB Kunjamma, SK Ha… - Immunity, 2020 - cell.com
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous
system. While work has focused on myelin and axon loss in MS, less is known about …
system. While work has focused on myelin and axon loss in MS, less is known about …