Objective: High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) is a safe
and effective treatment for major depression. However, its utility as a strategy to accelerate …

The link between mitochondria and major depressive disorder (MDD) is increasingly
evident, underscored both by mitochondria's involvement in many mechanisms identified in …

A significant proportion of depressed patients eventually present with treatment‐
resistant/refractory major depression (TRD), a debilitating condition that imposes significant …

ETHNOPHARMACOLOGICAL RELEVANCE: Several species of Annona (Annonaceae) are
used in traditional Mexican medicine by their anti-anxiety, anticonvulsant and tranquilizing …

Background: The large majority of depressed patients fail to remit on the first antidepressant
prescribed. These patients with residual symptoms have higher relapse rates and poorer …

It has been discovered that administering a combi nation of agents, bupropion and (at least
one) serotonin 5-HT, partial agonist, such as azapirones, preferably bus pirone, provides …

Method: In this randomized double-blind placebo-controlled study, patients were assessed
in the outpatient clinics of 2 large hospitals from November 2011 to January 2012. Forty …

Introduction The aim of this study was to describe the number and type of drugs used to treat
depressive disorders in inpatient psychiatry and to analyse the determinants of potential …

The phenomenon of treatment-resistant depression (TRD), described as the occurrence of
an inadequate response after an adequate treatment with antidepressant agents (in terms of …

Treatment for major depressive disorder does not achieve remission in about 50% of
patients following 2 treatment trials. Researchers conducted the Sequenced Treatment …