Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …

Insertion sequences (ISs) constitute an important component of most bacterial genomes.
Over 500 individual ISs have been described in the literature to date, and many more are …

This chapter is an update of a survey of insertion sequences (ISs) published in 1998.
Researchers have retained the same basic structure: a first section including some key …

Mobile genetic elements (MGEs) play a central role in the evolution of bacterial genomes.
Transposable elements (TE: transposons and insertion sequences) represent an important …

We provide here an overview of our present understanding of the distribution of different
insertion sequences (ISs) within bacterial genomes (both chromosomes and plasmids). This …

The bacterial insertion sequence, IS911, is a member of the large IS3family. It transposes
using a mechanism known as Copy‐out–Paste‐in. This is a major transposition pathway as …

Limiting the spread of synthetic genetic information outside of the intended use is essential
for applications where biocontainment is critical. In particular, biocontainment of engineered …

An efficient and quantitative method to analyze the transposition of various insertion
sequence (IS) elements in Burkholderia multivorans ATCC 17616 was devised. pGEN500, a …

Movement of transposable elements is often accompanied by replication to ensure their
proliferation. Replication is associated with both major classes of transposition mechanisms …

The coexistence of transposons with their hosts depends largely on transposition levels
being tightly regulated to limit the mutagenic burden associated with frequent transposition …