Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …

Diabetes mellitus (DM) is a serious medical problem affecting millions of peoples worldwide,
and has a great socio-economic impacts. Cytokines possess a pivotal role in modulation of …

Background and aim: Interleukin (IL) 17 is a cytokine which exerts strong proinflammatory
activities. In this study we evaluated changes in IL-17 expression in the inflamed mucosa …

Interleukin-17 (IL-17) is a pro-inflammatory cytokine secreted by activated T-cells. Recently
discovered related molecules are forming a family of cytokines, the IL-17 family. The …

Osteoarthritis (OA) is the leading cause of function loss and disability among the elderly, with
significant burden on the individual and society. It is a severe disease for its high disability …

IL-17 (interleukin-17), a hallmark cytokine of Th17 (T-helper 17) cells, plays critical roles in
host defence against bacterial and fungal infections, as well as in the pathogenesis of …

Summary Uncommitted (naive) murine CD4+ T helper cells (Thp) can be induced to
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …

Abstract Interleukin-17 (IL-17) and IL-17-producing cells have been shown to play important
roles in inflammation and the immune response. IL-17 is believed to be mainly produced by …

For almost two decades, the Th1/Th2 paradigm has offered a productive conceptual
framework for investigating the pathogenesis of periodontitis. However, as with many other …