Challenges and strategies for ocular posterior diseases therapy via non-invasive advanced drug delivery

Q Qi, Y Wei, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2023 - Elsevier
Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

[HTML][HTML] Role of flavonoids in age-related macular degeneration

M Sun, T Yu, J Zhao, X Zhu, W Xin, F Zhang… - Biomedicine & …, 2023 - Elsevier
A common eye disorder known as age-related macular degeneration (AMD) eventually
results in blindness and vision loss. AMD has a complicated and poorly understood …

Mesenchymal stem cell exosomes as nanotherapeutics for dry age-related macular degeneration

Y Tang, Y Kang, X Zhang, C Cheng - Journal of Controlled Release, 2023 - Elsevier
Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is a major factor in the
pathogenesis of dry age-related macular degeneration (AMD). Although the therapeutic …

Development of injectable hyaluronic acid-based hydrogels with antioxidant activity for the treatment of corneal neovascularization

L Long, Z Ge, F Zhang, R Dong, L Yang, Z Chen… - Chemical Engineering …, 2023 - Elsevier
Corneal neovascularization (CNV) is a condition that can severely adversely affect corneal
transparency, culminating in visual disturbances and potential blindness. The need to …

Topical Application of Cell-Penetrating Peptide Modified Anti-VEGF Drug Alleviated Choroidal Neovascularization in Mice

W Hu, W Cai, Y Wu, C Ren, D Yu, T Li… - International Journal …, 2024 - Taylor & Francis
Background Age-related macular degeneration (AMD) stands as the foremost cause of
irreversible central vision impairment, marked by choroidal neovascularization (CNV). The …

Recent Advances in Nanomedicine for Ocular Fundus Neovascularization Disease Management

Y Zhou, M Xu, W Shen, Y Xu, A Shao… - Advanced …, 2024 - Wiley Online Library
As an indispensable part of the human sensory system, visual acuity may be impaired and
even develop into irreversible blindness due to various ocular pathologies. Among ocular …

Robust integration of light-driven carbon quantum dots with bacterial cellulose enables excellent mechanical and antibacterial biodegradable yarn

Z Li, J Ai, D Wu, Y Yu, L Xie, H Ke, Q Wang… - International Journal of …, 2024 - Elsevier
Due to the overuse of antimicrobial drugs, bacterial resistance became an urgent problem to
be solved. In this study, carbon quantum dots (CQDs) with high photodynamic antibacterial …

Intravitreal injectable hydrogel rods with long-acting bevacizumab delivery to the retina

S Lee, HK Hong, JS Song, S Im Jeong, JY Chung… - Acta Biomaterialia, 2023 - Elsevier
Retinal vascular diseases such as neovascular age-related macular degeneration (nAMD)
are the leading cause of blindness worldwide. They can be treated with intravitreal injections …

An Overview of the Potential of Food-Based Carbon Dots for Biomedical Applications

CY Wang, N Ndraha, RS Wu, HY Liu, SW Lin… - International Journal of …, 2023 - mdpi.com
Food-based carbon dots (CDs) hold significant importance across various fields, ranging
from biomedical applications to environmental and food industries. These CDs offer unique …

Intraocular delivery considerations of ocular biologic products and key preclinical determinations

P Hughes, HM Rivers, V Bantseev… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Ophthalmic diseases of the retina are a significant cause of vision loss globally.
Despite much progress, there remains an unmet need for durable, long-acting treatment …