Hypertension as cardiovascular risk factor in chronic kidney disease

M Burnier, A Damianaki - Circulation research, 2023 - Am Heart Assoc
Hypertension is the leading modifiable cause of premature death and hence one of the
global targets of World Health Organization for prevention. Hypertension also affects the …

Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging

I Sack - Nature Reviews Physics, 2023 - nature.com
Magnetic resonance elastography (MRE) is a versatile imaging technique for mapping the
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …

[HTML][HTML] TXNIP: A key protein in the cellular stress response pathway and a potential therapeutic target

EH Choi, SJ Park - Experimental & Molecular Medicine, 2023 - nature.com
Abstract Thioredoxin-interacting protein (TXNIP), which is also known as thioredoxin-binding
protein 2 (TBP2), directly interacts with the major antioxidant protein thioredoxin (TRX) and …

[HTML][HTML] Global Economic Burden Associated with chronic kidney disease: a pragmatic review of medical costs for the Inside CKD Research Programme

V Jha, SMG Al-Ghamdi, G Li, MS Wu, P Stafylas… - Advances in …, 2023 - Springer
Introduction Chronic kidney disease (CKD) is a progressive disease of growing prevalence,
posing serious concerns for global public health. While the economic burden of CKD is …

[HTML][HTML] Causal effects of gut microbiota on the risk of chronic kidney disease: a Mendelian randomization study

M Luo, J Cai, S Luo, X Hong, L Xu, H Lin… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Previous studies have reported that gut microbiota is associated with an
increased risk of chronic kidney disease (CKD) progression. However, whether gut …

[HTML][HTML] AI-Powered Renal Diet Support: Performance of ChatGPT, Bard AI, and Bing Chat

A Qarajeh, S Tangpanithandee, C Thongprayoon… - Clinics and …, 2023 - mdpi.com
Patients with chronic kidney disease (CKD) necessitate specialized renal diets to prevent
complications such as hyperkalemia and hyperphosphatemia. A comprehensive …

[HTML][HTML] The interplay between immune and metabolic pathways in kidney disease

L Qu, B Jiao - Cells, 2023 - mdpi.com
Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the
global population. Kidney disease encompasses a diverse group of disorders that vary in …

[HTML][HTML] Structural and functional changes in aging kidneys

J Dybiec, M Szlagor, E Młynarska, J Rysz… - International Journal of …, 2022 - mdpi.com
The renal condition is one of the crucial predictors of longevity; therefore, early diagnosis of
any dysfunction plays an important role. Kidneys are highly susceptible to the aging process …

Artificial intelligence-assisted repurposing of lubiprostone alleviates tubulointerstitial fibrosis

A Samantasinghar, F Ahmed, CSA Rahim, KH Kim… - Translational …, 2023 - Elsevier
Tubulointerstitial fibrosis (TIF) is the most prominent cause which leads to chronic kidney
disease (CKD) and end-stage renal failure. Despite extensive research, there have been …

Gender-based research underscores sex differences in biological processes, clinical disorders and pharmacological interventions

SR Bernstein, C Kelleher, RA Khalil - Biochemical Pharmacology, 2023 - Elsevier
Earlier research has presumed that the male and female biology is similar in most organs
except the reproductive system, leading to major misconceptions in research interpretations …