Radical oxygen species: an important breakthrough point for botanical drugs to regulate oxidative stress and treat the disorder of glycolipid metabolism

M Luo, Y Zheng, S Tang, L Gu, Y Zhu, R Ying… - Frontiers in …, 2023 - frontiersin.org
Background: The incidence of glycolipid metabolic diseases is extremely high worldwide,
which greatly hinders people's life expectancy and patients' quality of life. Oxidative stress …

Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism

Y Zhang, Y Gu, J Jiang, X Cui, S Cheng, L Liu… - npj Science of …, 2022 - nature.com
Stigmasterol (ST) has been shown to improve both lipid and bile acid (BA) metabolism.
However, the mechanism (s) by which ST prevents dyslipidemia via BA metabolism, and the …

Antioxidative hypoglycemic herbal medicines with in vivo and in vitro activity against C-reactive protein; a systematic review

M Mirahmad, S Mohseni, O Tabatabaei-Malazy… - Phytomedicine, 2023 - Elsevier
Background Inflammation is a double-edged sword in the pathophysiology of chronic
diseases, such as type 2 diabetes mellitus (T2DM). The global rise in the prevalence of …

Diaphragma juglandis extracts modifies the gut microbiota during prevention of type 2 diabetes in rats

F Zhang, D Chen, L Zhang, Q Zhao, Y Ma… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The diaphragma juglandis (DJ) comes from the wooden
septum in the core of Juglans regia L, also known as the walnut septum. In Iranian traditional …

Lycopene modulates placental health and fetal development under high‐fat diet during pregnancy of rats

S Sun, C Cao, J Li, Q Meng, B Cheng… - Molecular Nutrition & …, 2021 - Wiley Online Library
Lycopene plays an important role in improving immunity, promoting antioxidant capacity,
and regulating fat metabolism. The placenta, an important organ for nutrients exchange …

Molecular and electrophysiological role of diabetes-associated circulating inflammatory factors in cardiac arrhythmia remodeling in a metabolic-induced model of type …

J Zayas-Arrabal, A Alquiza, E Tuncay, B Turan… - International Journal of …, 2021 - mdpi.com
Background: Diabetic patients have prolonged cardiac repolarization and higher risk of
arrhythmia. Besides, diabetes activates the innate immune system, resulting in higher levels …

Inhibition of Lipid Accumulation and Adipokine Levels in Maturing Adipocytes by Bauhinia rufescens (Lam.) Stem Bark Extract Loaded Titanium Oxide Nanoparticles

GM Alshammari, AEGA Yagoub, P Subash-Babu… - Molecules, 2021 - mdpi.com
The present study reports a cost-effective, environmentally friendly method to increase the
bioavailability and bio-efficacy of B. rufescens stem bark extract in the biological system via …

Industrial importance seed kernel of Buchanania lanzan in contributing antioxidant, antidiabetic, and anticholinesterase activities

N Meher, B Kisan, SK Swain, AK Sahoo - Food Bioscience, 2024 - Elsevier
This study aimed to evaluate the antioxidant, antidiabetic, and anticholinesterase activities of
Buchanania lanzan Spreng seeds. The therapeutic significance of phytochemicals …

Zinc and L-carnitine combination with or without methotrexate prevents intestinal toxicity during arthritis treatment via Nrf2/Sirt1/Foxo3 pathways: an In vivo and …

R Katturajan, S Evan Prince - Inflammopharmacology, 2023 - Springer
Methotrexate (MTX) is an antifolate that is inescapable and widely used to treat autoimmune
diseases and is the gold standard medicine for the arthritic condition. Despite its importance …

Homalium zeylanicum attenuates streptozotocin-induced hyperglycemia and cellular stress in experimental rats via attenuation of oxidative stress imparts …

D Rout, UC Dash, S Kanhar, SK Swain… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Homalium zeylanicum (Gardner) Benth
(Salicaceae) leaves are being used as folklore medicine to treat diabetes by the local folk of …