Allosteric regulation plays an important role in many biological processes, such as signal
transduction, transcriptional regulation, and metabolism. Allostery is rooted in the …

Connecting dynamics to structural data from diverse experimental sources, molecular
dynamics simulations permit the exploration of biological phenomena in unparalleled detail …

Motile Escherichia coli cells track gradients of attractant and repellent chemicals in their
environment with transmembrane chemoreceptor proteins. These receptors operate in …

The extraordinary capacity of Agrobacterium to transfer its genetic material to host cell
makes it evolve from phytopathogen to a powerful transgenic vector. Agrobacterium …

How can single cells without nervous systems perform complex behaviours such as
habituation, associative learning and decision making, which are considered the hallmark of …

Chemotactic responses in bacteria require large, highly ordered arrays of sensory proteins
to mediate the signal transduction that ultimately controls cell motility. A mechanistic …

Here we review recent studies of mechanical metamaterials originating from or closely
related to marginally jammed solids. Unlike previous approaches mainly focusing on the …

The Escherichia coli chemosensory system consists of large arrays of transmembrane
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …

Motile bacteria sense chemical gradients with transmembrane receptors organised in
supramolecular signalling arrays. Understanding stimulus detection and transmission at the …

In most signal transduction systems, coupling or scaffold proteins establish crucial
connections between receptors and histidine kinases. These connections are important for …