Chalcone derivatives: Role in anticancer therapy

Y Ouyang, J Li, X Chen, X Fu, S Sun, Q Wu - Biomolecules, 2021 - mdpi.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship

F Gao, G Huang, J Xiao - Medicinal Research Reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Pyrazoline hybrids as promising anticancer agents: An up-to-date overview

D Matiadis, M Sagnou - International Journal of Molecular Sciences, 2020 - mdpi.com
Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Magnetic chitosan-copper nanocomposite: A plant assembled catalyst for the synthesis of amino-and N-sulfonyl tetrazoles in eco-friendly media

N Motahharifar, M Nasrollahzadeh… - Carbohydrate …, 2020 - Elsevier
A greener, cost efficient and simple method is described to prepare copper nanoparticles
(NPs) immobilized on the magnetic chitosan (one of the more versatile polysaccharides) …

Tetrazoles for biomedicine

EA Popova, RE Trifonov… - Russian Chemical …, 2019 - iopscience.iop.org
The tetrazole ring is an important pharmacophore. It is a structural component in many
drugs, drug candidates (or lead compounds) and various biochemical reagents. This review …

Tetrazole hybrids with potential anticancer activity

J Zhang, S Wang, Y Ba, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Cancer is one of the main causes of death throughout the world. The anticancer agents are
indispensable for the treatment of various cancers, but most of them currently on the market …

Anticancer activity of natural and synthetic chalcones

T Constantinescu, CN Lungu - International journal of molecular sciences, 2021 - mdpi.com
Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and
inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells …

One-pot and two-pot synthesis of chalcone based mono and bis-pyrazolines

S Farooq, Z Ngaini - Tetrahedron Letters, 2020 - Elsevier
Pyrazoline is an important heterocyclic compound in organic and pharmaceutical industry.
The pyrazoline-based compounds are intensively used in medicines and agricultural …

An overview on synthesis and biological activity of chalcone derived pyrazolines

A Tiwari, A Bendi, AS Bhathiwal - ChemistrySelect, 2021 - Wiley Online Library
Chalcones are α, β unsaturated aromatic ketones having enone moiety and exhibit a wide
array of pharmaceutical and biological activities. Chalcones possess a wide range of …

Functionalization of chitosan by grafting Cu (II)-5-amino-1H-tetrazole complex as a magnetically recyclable catalyst for CN coupling reaction

M Nasrollahzadeh, N Motahharifar, M Sajjadi… - Inorganic Chemistry …, 2022 - Elsevier
The functionalization of chitosan (as a linear polysaccharide) with a copper complex to
expand the areas of its potential applications is an important scientific task. The present work …