Several lines of evidence support a role of the immune system in headache pathogenesis,
with particular regard to migraine. Firstly, alterations in cytokine profile and in lymphocyte …

Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease and is extremely
heterogeneous in terms of immunological features and clinical manifestations. This …

Objective A limited range of neuropsychiatric symptoms have been reported in systemic
autoimmune rheumatic diseases (SARDs), with varied symptom prevalence. This study …

Background Neuropsychiatric systemic lupus erythematosus (NPSLE), with various
morbidities and multiple manifestations in the central nervous system, remains a limited …

Introduction Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset
systemic lupus erythematosus (jSLE). Aim To investigate the prevalence, demographic and …

Objectives A survey conducted by the Spanish Lupus Federation (FELUPUS) shows the
results on perceptions and experiences of the people who live with lupus in Spain. The …

Objective Neurological manifestations of autoimmune connective tissue diseases (CTD) are
poorly understood and difficult to diagnose. We here aimed to address this shortcoming by …

Nowadays, osteoarthritis (OA), a common, multifactorial musculoskeletal disease, is
considered to have a low-grade inflammatory pathogenetic component. Lately …

Background Since dysregulation of total Interleukin (IL)-18 and IL-18 binding protein (IL-
18BP) may participate in systemic lupus erythematosus (SLE) and contribute to the …

Central nervous system (CNS) involvement in autoimmune rheumatic diseases represents a
significant challenge for clinicians across all specialties. While most reviews on the subject …