Skin injuries across the body continue to disrupt everyday life for millions of patients and
result in prolonged hospital stays, infection, and death. Advances in wound healing devices …

The enhancement of immune responses upon treatment with immune checkpoint inhibitors
can have the desired outcome of reinvigorating antitumour immune surveillance, but often at …

Most of what we know about adaptive immunity has come from inbred mouse studies, using
methods that are often difficult or impossible to confirm in humans. In addition, vaccine …

Recombinant adeno-associated virus (AAV) is the leading vector for gene therapy in the
retina. As non-pathogenic, non-integrating, replication deficient vector, the recombinant virus …

Oncolytic virus therapy can increase the immunogenicity of tumors and remodel the
immunosuppressive tumor microenvironment, leading to an increased antitumor response to …

The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect
consequences may include maintenance of homeostasis through prevention of infection …

Significance: Wound healing is a complex and dynamic series of events influenced by a
variety of intrinsic and extrinsic factors. Problematic wounds, particularly chronic wounds …

Immunotherapy remains more effective for hematologic tumors than for solid tumors. One of
the main challenges to immunotherapy of solid tumors is the immunosuppressive …

Current treatment strategies for inflammatory bowel disease (IBD) seek to alleviate the
undesirable symptoms of the disorder. Despite the higher specificity of newer generation …

The lymph node is a highly structured organ that mediates the body's adaptive immune
response to antigens and other foreign particles. Central to its function is the distinct spatial …