The gut microbiome and Alzheimer's disease: Complex and bidirectional interactions

R Tarawneh, E Penhos - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Structural and functional alterations to the gut microbiome, referred to as gut dysbiosis, have
emerged as potential key mediators of neurodegeneration and Alzheimer disease (AD) …

Environmental enrichment effects on the brain-derived neurotrophic factor expression in healthy condition, Alzheimer's disease, and other neurodegenerative …

D Cutuli, E Landolfo, L Petrosini… - Journal of Alzheimer's …, 2022 - content.iospress.com
Brain-derived neurotrophic factor (BDNF), a protein belonging to the neurotrophin family, is
known to be heavily involved in synaptic plasticity processes that support brain …

Long-term exercise from adolescence to adulthood reduces anxiety-and depression-like behaviors following maternal immune activation in offspring

S Rahimi, M Peeri, MA Azarbayjani, L Anoosheh… - Physiology & …, 2020 - Elsevier
Maternal immune activation is an environmental risk factor for the development of
neuropsychiatric disorders such as anxiety and depression later in life. There is an urgent …

Silymarin sex-dependently improves cognitive functions and alters TNF-α, BDNF, and glutamate in the hippocampus of mice with mild traumatic brain injury

G Shokouhi, M Kosari-Nasab, AA Salari - Life Sciences, 2020 - Elsevier
Aims Mild traumatic brain injury (mTBI) is an important risk factor for cognitive impairment.
Despite intense efforts to develop efficient treatments, the current therapies are not often …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with …

S Naghibi, MS Joneydi, A Barzegari… - Physiology & …, 2021 - Elsevier
Alzheimer's disease (AD) is associated with increased depression-related behaviours.
Previous studies have reported a greater risk of AD and depression in women. In recent …

The combination of fluoxetine and environmental enrichment reduces postpartum stress-related behaviors through the oxytocinergic system and HPA axis in mice

H Bashiri, DJ Houwing, JR Homberg, AA Salari - Scientific Reports, 2021 - nature.com
Gestational stress can increase postpartum depression in women. To treat maternal
depression, fluoxetine (FLX) is most commonly prescribed. While FLX may be effective for …

Swimming exercise attenuates anxiety-like behavior by reducing brain oxidative stress in type 2 diabetic mice

P Matinfar, M Peeri, MA Azarbayjani - Physiology & Behavior, 2021 - Elsevier
Anxiety-related behaviors are among the most prevalent psychiatric disorders in patients
with type 2 diabetes (T2D). The protective effect of exercise on neuropsychiatric disorders …

Implications of physical exercise on episodic memory and anxiety: The role of the serotonergic system

R Illesca-Matus, NM Ardiles, F Munoz… - International Journal of …, 2023 - mdpi.com
There is a growing interest in investigating the effects of physical exercise on cognitive
performance, particularly episodic memory. Similarly, an increasing number of studies in …

Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer's disease of 3× Tg mice

SS Park, HS Park, CJ Kim, SS Baek… - Journal of Applied …, 2022 - journals.physiology.org
Alzheimer's disease (AD) is a progressive degenerative brain disease and the primary
cause of dementia. At an early stage, AD is generally characterized by short-term memory …