Recent advancements in the targeted delivery of etoposide nanomedicine for cancer therapy: A comprehensive review

S Fathi-Karkan, R Arshad, A Rahdar… - European Journal of …, 2023 - Elsevier
Etoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be
administered more effectively and efficiently due to nanomedicine. The therapeutic …

Lipid and polymeric nanoparticles: successful strategies for nose-to-Brain drug delivery in the treatment of depression and anxiety disorders

M Alberto, AC Paiva-Santos, F Veiga, PC Pires - Pharmaceutics, 2022 - mdpi.com
Intranasal administration has gained an increasing interest for brain drug delivery since it
allows direct transport through neuronal pathways, which can be quite advantageous for …

[HTML][HTML] Riluzole-loaded lipid nanoparticles for brain delivery: Preparation, optimization and characterization

MI Teixeira, CM Lopes, H Gonçalves, J Catita… - Journal of Molecular …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, with a median
survival of only 2 to 4 years. Riluzole, a drug commonly used in the management of ALS …

Angiopep-2-Functionalized Lipid Cubosomes for Blood–Brain Barrier Crossing and Glioblastoma Treatment

X Cai, A Refaat, PY Gan, B Fan, H Yu… - … Applied Materials & …, 2024 - ACS Publications
Glioblastoma multiforme (GBM) is an aggressive brain cancer with high malignancy and
resistance to conventional treatments, resulting in a bleak prognosis. Nanoparticles offer a …

The battle of lipid-based nanocarriers against blood-brain barrier: A critical review

KK Abla, MM Mehanna - Journal of Drug Targeting, 2023 - Taylor & Francis
Central nervous system integrity is the state of brain functioning across sensory, cognitive,
emotional-social behaviors, and motor domains, allowing a person to realise his full …

[HTML][HTML] Nanosystems for brain targeting of antipsychotic drugs: An update on the most promising nanocarriers for increased bioavailability and therapeutic efficacy

MD Ferreira, J Duarte, F Veiga, AC Paiva-Santos… - Pharmaceutics, 2023 - mdpi.com
Orally administered antipsychotic drugs are the first-line treatment for psychotic disorders,
such as schizophrenia and bipolar disorder. Nevertheless, adverse drug reactions …

Recent advancement of bio-inspired nanoparticles in cancer theragnostic

D Tripathi, K Hajra, D Maity - Journal of Nanotheranostics, 2023 - mdpi.com
The introduction of cancer therapeutics and nanotechnology has resulted in a paradigm shift
from conventional therapy to precision medicine. Nanotechnology, an interdisciplinary field …

The interaction between particles and vascular endothelium in blood flow

X Li, J Zou, Z He, Y Sun, X Song, W He - Advanced Drug Delivery Reviews, 2024 - Elsevier
Particle-based drug delivery systems have shown promising application potential to treat
human diseases; however, an incomplete understanding of their interactions with vascular …

[HTML][HTML] Nanosystems, Drug Molecule functionalization and intranasal delivery: an update on the most promising strategies for increasing the therapeutic efficacy of …

JL Antunes, J Amado, F Veiga, AC Paiva-Santos… - Pharmaceutics, 2023 - mdpi.com
Depression and anxiety are high incidence and debilitating psychiatric disorders, usually
treated by antidepressant or anxiolytic drug administration, respectively. Nevertheless …

The major hypotheses of Alzheimer's disease: related nanotechnology-based approaches for its diagnosis and treatment

C Cáceres, B Heusser, A Garnham, E Moczko - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a well-known chronic neurodegenerative disorder that leads to
the progressive death of brain cells, resulting in memory loss and the loss of other critical …