[HTML][HTML] Neuroinflammation: friend and foe for ischemic stroke

RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

[HTML][HTML] The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological …

P Gong, Y Liu, Y Gong, G Chen, X Zhang… - Journal of …, 2021 - Springer
Background and purpose To investigate the association of neutrophil to lymphocyte ratio
(NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) with post …

[HTML][HTML] Damage to dopaminergic neurons by oxidative stress in Parkinson's disease

JD Guo, X Zhao, Y Li, GR Li… - International …, 2018 - build.spandidos-publications.com
Oxidative stress is increasingly recognized as a central event contributing to the
degeneration of dopaminergic neurons in the pathogenesis of Parkinson's disease (PD) …

[HTML][HTML] Necroptosis: a novel pathway in neuroinflammation

Z Yu, N Jiang, W Su, Y Zhuo - Frontiers in pharmacology, 2021 - frontiersin.org
Neuroinflammation is a complex inflammatory process in the nervous system that is
expected to play a significant role in neurological diseases. Necroptosis is a kind of necrosis …

The role of oxidative stress in Parkinson's disease

V Dias, E Junn, MM Mouradian - Journal of Parkinson's …, 2013 - content.iospress.com
Oxidative stress plays an important role in the degeneration of dopaminergic neurons in
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …

[HTML][HTML] Metabolic reprograming of microglia in the regulation of the innate inflammatory response

C Lauro, C Limatola - Frontiers in Immunology, 2020 - frontiersin.org
Microglia sustain normal brain functions continuously monitoring cerebral parenchyma to
detect neuronal activities and alteration of homeostatic processes. The metabolic pathways …

[HTML][HTML] Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke

P Xu, X Zhang, Q Liu, Y Xie, X Shi, J Chen, Y Li… - Cell death & …, 2019 - nature.com
Neuroinflammation is initiated in response to ischemic stroke, generally with the hallmarks of
microglial activation and collateral brain injury contributed by robust inflammatory effects …

[HTML][HTML] Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms

C Stonesifer, S Corey, S Ghanekar, Z Diamandis… - Progress in …, 2017 - Elsevier
Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

[HTML][HTML] Intestinal microbial dysbiosis aggravates the progression of Alzheimer's disease in Drosophila

SC Wu, ZS Cao, KM Chang, JL Juang - Nature communications, 2017 - nature.com
Neuroinflammation caused by local deposits of Aβ42 in the brain is key for the pathogenesis
and progression of Alzheimer's disease. However, inflammation in the brain is not always a …