Cannabinoids as immune system modulators: Cannabidiol potential therapeutic approaches and limitations

A Aziz, LC Nguyen, L Oumeslakht… - Cannabis and …, 2023 - liebertpub.com
Introduction: Cannabidiol (CBD) is the second most abundant Phytocannabinoid in
Cannabis extracts. CBD has a binding affinity for several cannabinoid and cannabinoid …

Biological effects of cannabidiol on human cancer cells: Systematic review of the literature

C Valenti, M Billi, GL Pancrazi, E Calabria… - Pharmacological …, 2022 - Elsevier
This systematic review examine the biological effects of CBD, a major component of
therapeutic Cannabis, on human pathological and cancer cell populations of integumentary …

Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor 2-dependent mechanism in human colorectal cancer cells

HS Lee, G Tamia, HJ Song, D Amarakoon… - International …, 2022 - Elsevier
Colorectal cancer is the third leading cause of cancer incidence and mortality in the United
States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis …

Role of cannabidiol for improvement of the quality of life in cancer patients: potential and challenges

R Green, R Khalil, SS Mohapatra… - International Journal of …, 2022 - mdpi.com
There is currently a growing interest in the use of cannabidiol (CBD) to alleviate the
symptoms caused by cancer, including pain, sleep disruption, and anxiety. CBD is often self …

Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells

H Koltai, N Shalev - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most lethal gynecological malignancy. Cancer stem
cells have been implicated in tumor initiation, progression, and invasion, as well as tumor …

Antitumor mechanism of cannabidiol hidden behind cancer hallmarks

C Yan, Y Li, H Liu, D Chen, J Wu - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Cannabinoids have been utilized for recreational and therapeutic purposes for over 4,000
years. As the primary ingredient in exogenous cannabinoids, Cannabidiol (CBD) has drawn …

An examination of the anti-cancer properties of plant cannabinoids in preclinical models of mesothelioma

EK Colvin, AL Hudson, LL Anderson, RP Kumar… - Cancers, 2022 - mdpi.com
Simple Summary Mesothelioma is a deadly disease with few treatment options.
Phytocannabinoids derived from the cannabis plant are garnering interest for their anti …

Cannabinoid cancer biology and prevention

SD McAllister, ME Abood, J Califano… - JNCI …, 2021 - academic.oup.com
Plant-based, synthetic, and endogenous cannabinoids have been shown to control a
diverse array of biological processes, including regulation of cell fate across cancers. Their …

Role of Cannabinoids in Oral Cancer

B Cretu, A Zamfir, S Bucurica, AE Scheau… - International Journal of …, 2024 - mdpi.com
Cannabinoids have incited scientific interest in different conditions, including malignancy,
due to increased exposure to cannabis. Furthermore, cannabinoids are increasingly used to …

Cannabidiol inhibits RAD51 and sensitizes glioblastoma to temozolomide in multiple orthotopic tumor models

L Soroceanu, E Singer, P Dighe… - Neuro-Oncology …, 2022 - academic.oup.com
Background Cannabidiol (CBD), a nonpsychoactive cannabinoid with a low toxicity profile,
has been shown to produce antitumor activity across cancers in part through selective …