The androgen-thyroid hormone crosstalk in prostate cancer and the clinical implications

S Torabinejad, C Miro, B Barone… - European thyroid …, 2023 - etj.bioscientifica.com
There is increasing evidence that thyroid hormones (THs) work in an integrative fashion with
androgen receptors (ARs) to regulate gonadal differentiation and reproductive function …

The clinical relevance of hypothyroidism in patients with solid non-thyroid cancer: a tantalizing conundrum

MV Deligiorgi, DT Trafalis - Journal of Clinical Medicine, 2022 - mdpi.com
Hypothyroidism in patients with solid non-thyroid cancer is a tantalizing entity, integrating an
intriguing thyroid hormones (THs)–cancer association with the complexity of hypothyroidism …

Genetically predicted alterations in thyroid function are associated with the risk of benign prostatic disease

Y Huang, C Chen, W Zhou, Q Zhang, Y Zhao… - Frontiers in …, 2023 - frontiersin.org
Background Benign prostatic diseases (BPDs), such as benign prostate hyperplasia (BPH)
and prostatitis, harm the quality of life of affected patients. However, observational studies …

Pre-diagnosis thyroid hormone dysfunction is associated with cancer mortality

E Krashin, B Silverman, DM Steinberg… - Endocrine-Related …, 2021 - erc.bioscientifica.com
Research on the association between thyroid hormone levels and cancer mortality remains
limited and inconclusive. We determined the relation of thyroid stimulating hormone (TSH) …

The association between three prevalent autoimmune disorders and the likelihood of developing prostate cancer: a Mendelian randomization study

X Deng, S Sun, W Yao, P Yue, F Guo, Y Wang… - Scientific Reports, 2024 - nature.com
Numerous studies establish a significant correlation between autoimmune disorders (AIDs)
and prostate cancer (PCa). Our Mendelian randomization (MR) analysis investigates the …

Hyperthyroidism and the risk of non-thyroid cancer: a Danish register-based long-term follow-up study

T Riis, SJ Bonnema, TH Brix… - European Thyroid …, 2024 - etj.bioscientifica.com
Objective Cancer is the second most common cause of death worldwide. It is currently
debated whether thyroid dysfunction is a modifiable cancer risk factor. Our aim was to …

Protective effect of higher free thyroxine levels within the reference range on biliary tract cancer risk: a multivariable mendelian randomization and mediation analysis

Y Chen, H Dong, B Qu, X Ma, LL Lu - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Hepatobiliary cancer (HBC), including hepatocellular carcinoma (HCC) and
biliary tract cancer (BTC), is currently one of the malignant tumors that mainly cause human …

Prostate gland as a target organ of thyroid hormones: advances and controversies

B Anguiano, CM de Oca… - Endocrine …, 2022 - ec.bioscientifica.com
Thyroid hormones are involved in the development and function of the male reproductive
system, but their effects on the prostate have been poorly studied. This work reviews studies …

Distinguishing EGFR mutant subtypes in stage IA non-small cell lung cancer using the presence status of ground glass opacity and final histologic classification: a …

J Qiu, Z Ma, R Li, C Qu, K Wang, B Liu, Y Tian… - Frontiers in …, 2023 - frontiersin.org
Background The progression of early stage non-small cell lung cancer (NSCLC) is closely
related to epidermal growth factor receptor (EGFR) mutation status. The purpose of this …

Genetically predicted thyroid function and risk of colorectal cancer: a bidirectional Mendelian randomization study

Q Du, Z Zheng, Y Wang, L Yang, Z Zhou - Journal of Cancer Research …, 2023 - Springer
Background Observational studies have reported an association between thyroid function
and colorectal cancer (CRC), with conflicting results. Elucidating the causal relationship …