Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …

Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Most animals and plants have associated microorganisms, collectively referred to as their
microbiomes, which can provide essential functions. Given their importance, host-associated …

Virtually all organisms are colonized by microbes. Average temperatures are rising because
of global climate change–accompanied by increases in extreme climatic events and heat …

Over the last 20 years, studies of Caenorhabditis elegans natural diversity have
demonstrated the power of quantitative genetic approaches to reveal the evolutionary …

Males of Caenorhabditis elegans provide a crucial practical tool in the laboratory, but, as the
rarer and more finicky sex, have not enjoyed the same depth of research attention as …

Caenorhabditis nematodes form an excellent model for studying how the mode of
reproduction affects genetic diversity, as some species reproduce via outcrossing whereas …

Genetic studies of complex traits in animals have been hindered by the need to generate,
maintain, and phenotype large panels of recombinant lines. We developed a new method …

Highlights•Caenorhabditis are versatile models for mitonuclear coevolution research.•C.
elegans mitochondrial DNA mutation spectra may reflect oxidative DNA damage.• …

Some epigenetic information can be transmitted between generations without changes in
the underlying DNA sequence. Changes in epigenetic regulators, termed epimutations, can …