Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Control of phagocytosis by microbial pathogens

E Uribe-Querol, C Rosales - Frontiers in immunology, 2017 - frontiersin.org
Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

[HTML][HTML] Antimicrobial peptides

L Zhang, RL Gallo - Current biology, 2016 - cell.com
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

Peptide antibiotics

REW Hancock, DS Chapple - Antimicrobial agents and …, 1999 - Am Soc Microbiol
Hundreds of peptide antibiotics have been described in the past half-century (20, 28, 35).
These fall into two classes, nonribosomally synthesized peptides, such as the gramicidins …

The roles of antimicrobial peptides in innate host defense

G Diamond, N Beckloff, A Weinberg… - Current …, 2009 - ingentaconnect.com
Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological
role in vivo has been proposed to be the elimination of pathogenic microorganisms …

Human neutrophils≠ murine neutrophils: Does it matter?

WM Nauseef - Immunological reviews, 2023 - Wiley Online Library
Human and murine neutrophils differ with respect to representation in blood, receptors,
nuclear morphology, signaling pathways, granule proteins, NADPH oxidase regulation …

Amphipathic, α‐helical antimicrobial peptides

A Tossi, L Sandri, A Giangaspero - Peptide Science, 2000 - Wiley Online Library
Gene‐encoded antimicrobial peptides are an important component of host defense in
animals ranging from insects to mammals. They do not target specific molecular receptors …

Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria

T Ayabe, DP Satchell, CL Wilson, WC Parks… - Nature …, 2000 - nature.com
Paneth cells in mouse small intestinal crypts secrete granules rich in microbicidal peptides
when exposed to bacteria or bacterial antigens. The dose-dependent secretion occurs …

Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils

J Turner, Y Cho, NN Dinh, AJ Waring… - Antimicrobial agents …, 1998 - Am Soc Microbiol
Human neutrophils contain two structurally distinct types of antimicrobial peptides, β-sheet
defensins (HNP-1 to HNP-4) and the α-helical peptide LL-37. We used radial diffusion …