Objective: To assess the efficacy of ritonavir-boosted protease inhibitor monotherapy.
Design and methods: Systematic review of all protease inhibitor-monotherapy studies …

Background: Prior attempts to reduce the number of drugs needed to maintain viral
suppression in patients with suppressed HIV replication while receiving three antiretroviral …

Objective: This study evaluated maintenance with lopinavir/ritonavir monotherapy vs.
continuing lopinavir/ritonavir and 2 nucleosides in HIV-infected patients with suppressed …

Background We hypothesized that the percent adherence to antiretroviral therapy necessary
to maintain HIV suppression would decrease with longer duration of viral suppression …

Objective To analyse the safety and efficacy of replacing the protease inhibitor (PI) by
nevirapine (NVP) in subjects experiencing a long-term control of virus replication under a …

Objectives To demonstrate the feasibility of a concentration-controlled approach to
combination antiretroviral therapy, and to compare the virological responses and safety of …

COMMENTARY fected cells τ was estimated from the 'shoulder'of the virusconcentration
decay curves to be about 1.25 days5. Our interpretation differs fundamentally from that …

The use of highly active antiretroviral therapy, the combination of at least three different
antiretroviral drugs for the treatment of HIV-1 infection, has greatly improved the prognosis …

Background Good adherence to antiretroviral therapy is necessary to achieve the best
virological response, lower the risk that drug resistance will develop, and reduce morbidity …

This randomized study evaluated the efficacy and tolerability of continued treatment with
protease inhibitor plus nucleoside-analogue combination regimens (n= 79) or a change to …