Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

AKI is a common clinical condition associated with the risk of developing CKD and ESKD.
Sepsis is the leading cause of AKI in the intensive care unit (ICU) and accounts for nearly …

AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

The pathogenesis of sepsis-associated acute kidney injury is complex and likely involves
perfusion alterations, a dysregulated inflammatory response, and bioenergetic …

Norepinephrine is the principal vasopressor used to restore blood pressure in sepsis, but its
effects on intrarenal oxygenation are unknown. To clarify this, we examined renal cortical …

Tissue hypoxia has been proposed as an important factor in the pathophysiology of both
chronic kidney disease (CKD) and acute kidney injury (AKI), initiating and propagating a …