Implication of coumarins towards central nervous system disorders
K Skalicka-Woźniak, IE Orhan, GA Cordell… - Pharmacological …, 2016 - Elsevier
Coumarins are widely distributed, plant-derived, 2 H-1-benzopyran-2-one derivatives which
have attracted intense interest in recent years as a result of their diverse and potent …
have attracted intense interest in recent years as a result of their diverse and potent …
Imperatorin: a review of its pharmacology, toxicity and pharmacokinetics
M Deng, L Xie, L Zhong, Y Liao, L Liu, X Li - European Journal of …, 2020 - Elsevier
As a naturally occurring furanocoumarin, the medicinal value of imperatorin has been
studied more and more. We hope to provide useful information for the further development of …
studied more and more. We hope to provide useful information for the further development of …
[HTML][HTML] Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice
B Budzynska, A Boguszewska-Czubara… - …, 2015 - Springer
Rationale Imperatorin, a naturally occurring furanocoumarin, inactivates gamma-
aminobutyric acid transaminase and inhibits acetylcholinesterase activity. Objectives The …
aminobutyric acid transaminase and inhibits acetylcholinesterase activity. Objectives The …
[HTML][HTML] Imperatorin–pharmacological meaning and analytical clues: profound investigation
E Kozioł, K Skalicka-Woźniak - Phytochemistry Reviews, 2016 - Springer
Imperatorin, a furanocoumarin derivative, has many documented pharmacological
properties which make it a candidate for possible drug development. In this review, the …
properties which make it a candidate for possible drug development. In this review, the …
Bioactivity-guided isolation of antimicrobial coumarins from Heracleum mantegazzianum Sommier & Levier (Apiaceae) fruits by high-performance counter-current …
M Walasek, A Grzegorczyk, A Malm… - Food chemistry, 2015 - Elsevier
An efficient strategy, based on bioassay-guided fractionation, high-performance liquid
chromatography (HPLC), and high-performance counter-current chromatography (HPCCC) …
chromatography (HPLC), and high-performance counter-current chromatography (HPCCC) …
Influence of diosmin treatment on the level of oxidative stress markers in patients with chronic venous insufficiency
M Feldo, M Woźniak, M Wójciak-Kosior… - Oxidative Medicine …, 2018 - Wiley Online Library
Oxidative stress plays an important role in the pathophysiology of many human disorders,
while antioxidants prevent the development of various adverse symptoms. Diosmin is a …
while antioxidants prevent the development of various adverse symptoms. Diosmin is a …
[HTML][HTML] Anxiolytic-like effects of ursolic acid in mice
Ursolic acid is a pentacyclic triterpenoid that possesses several biological and
neuropharmacological effects including antidepressant-like activity. Anxiety disorders …
neuropharmacological effects including antidepressant-like activity. Anxiety disorders …
Scopolamine-induced memory impairment is alleviated by xanthotoxin: Role of acetylcholinesterase and oxidative stress processes
K Skalicka-Wozniak, B Budzynska, G Biala… - ACS Chemical …, 2018 - ACS Publications
Xanthotoxin, popularly occurring furanocoumarin, which can be found in plants from the
Apiaceae family, was isolated from fruits of Pastinaca sativa L. by mean of high-performance …
Apiaceae family, was isolated from fruits of Pastinaca sativa L. by mean of high-performance …
[HTML][HTML] Effects of imperatorin in the cardiovascular system and cancer
MI Nasser, S Zhu, H Hu, H Huang, M Guo… - Biomedicine & …, 2019 - Elsevier
Patients with cancer survivors are at increased risk of cardiovascular disease (CVD). Cardio-
oncology has developed as a new discipline with the advances in cancer treatment. There …
oncology has developed as a new discipline with the advances in cancer treatment. There …
Ameliorative effect of imperatorin in chemically induced fibromyalgia: role of NMDA/NFkB mediated downstream signaling
Fibromyalgia (FM) is a chronic pain syndrome involving complex interplay of biogenic
amines and NMDA receptor mediated hypersensitization of nociceptive pathways. Clinical …
amines and NMDA receptor mediated hypersensitization of nociceptive pathways. Clinical …