SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice
K Meek, A Jutkowitz, L Allen, J Glover… - The Journal of …, 2009 - journals.aai.org
We have previously described DNA-dependent protein kinase (DNA-PKcs) mutations in
horses and dogs that result in deficits in V (D) J recombination, DNA repair, and SCID. In this …
horses and dogs that result in deficits in V (D) J recombination, DNA repair, and SCID. In this …
Inhibition of Ku70 in a high-glucose environment aggravates bupivacaine-induced dorsal root ganglion neurotoxicity
Y Wang, L Lai, W Guo, S Peng, R Liu, P Hong, G Wei… - Toxicology Letters, 2020 - Elsevier
Background Bupivacaine (BP) is commonly used as a local anaesthetic (LA) in the clinic, but
it can also cause neurotoxicity, especially in patients with diabetes. Previous studies have …
it can also cause neurotoxicity, especially in patients with diabetes. Previous studies have …
Targeting the epigenome as a therapeutic strategy for pancreatic tumors: noncoding RNAs and chromatin remodelers
SK Mungamuri - Theranostic Approach for Pancreatic Cancer, 2019 - Elsevier
Nucleosomes, which consist of DNA and histones, provide a secondary structure to the
eukaryotic chromatin. The nucleosomal organization of DNA affects cellular activities such …
eukaryotic chromatin. The nucleosomal organization of DNA affects cellular activities such …