Up-regulation of heme oxygenase 1 (HO-1) by ultraviolet A (UVA; 320–380nm) irradiation of
human skin cells protects them against oxidative stress. The role of Nrf2 in up-regulation of …

Background: Reactive oxygen species sustain tumorigenesis and cancer progression
through deregulated redox signalling which also sensitizes cancer cells to therapy …

Unlike most cytochrome P450 (CYP) enzymes, murine hepatic CYP2A5 is induced during
pathological conditions that result in liver injury including hepatotoxicity mediated by …

Arsenic, a naturally occurring toxic element, manifests in various chemical forms and is
widespread in the environment. Exposure to arsenic is a well-established risk factor for an …

Редокс-чувствительная сигнальная система Keap1/Nrf2/ARE играет важную роль в
поддержании клеточно-го гомеостаза при стрессовых, провоспалительных …

5′-AMP-activated protein kinase (AMPK) and the transcription factor nuclear factor
erythroid 2-related factor 2 (Nrf2) are main players in the cellular adaptive response to …

The activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is the most important
cellular defense mechanisms against oxidative attack. BTB and CNC homology-1 (Bach1) …

Background: The tumor microenvironment plays an important role in the progression of
cancer by mediating stromal–epithelial paracrine signaling, which can aberrantly modulate …

Ultraviolet A (UVA) radiation is an oxidizing agent that strongly induces the heme oxygenase
1 (HO-1) gene and expression of the protein in cultured human skin fibroblasts but weakly …

Oxidative stress plays an essential role in inflammation and fibrosis. Bach1 is an important
transcriptional repressor that acts by modulating oxidative stress and represents a potential …