A novel mechanism of Vildagliptin in regulating bone metabolism and mitigating osteoporosis

J He, D Zhao, B Peng, X Wang, S Wang, X Zhao… - International …, 2024 - Elsevier
Osteoporosis has become a global social problem with the tendency toward the aging
population. The challenge in managing osteoporosis is to develop new anti-osteoporosis …

[HTML][HTML] Bone and Extracellular Signal-Related Kinase 5 (ERK5)

L Wen, Z Liu, L Zhou, Z Liu, Q Li, B Geng, Y Xia - Biomolecules, 2024 - mdpi.com
Bones are vital for anchoring muscles, tendons, and ligaments, serving as a fundamental
element of the human skeletal structure. However, our understanding of bone development …

[PDF][PDF] Heraclenin promotes the osteogenic differentiation of bone marrow stromal cells by activating the RhoA/ROCK pathway

Z Yu, J Yuan, Y Yu - 2024 - hh.um.es
Background. Osteoporosis is a devastating skeletal disease, the pathogenesis of which is
related to abnormal bone metabolism, featured by the imbalance between osteoblastic bone …