Coalescence of droplets in a microwell driven by surface acoustic waves
Microwell arrays are amongst the most commonly used platforms for biochemical assays.
However, the coalescence of droplets that constitute the dispersed phase of suspensions …
However, the coalescence of droplets that constitute the dispersed phase of suspensions …
Advances in microfluidic 3D cell culture for preclinical drug development
M Russo, CM Cejas, G Pitingolo - Progress in Molecular Biology and …, 2022 - Elsevier
Drug development is often a very long, costly, and risky process due to the lack of reliability
in the preclinical studies. Traditional current preclinical models, mostly based on 2D cell …
in the preclinical studies. Traditional current preclinical models, mostly based on 2D cell …
Evaluation of BLG ability for binding to 5-FU and Irinotecan simultaneously under acidic condition: A spectroscopic, molecular docking and molecular dynamic …
U Sahebi, H Gholami, B Ghalandari… - Journal of Molecular …, 2021 - Elsevier
Drug delivery system optimization is an issue that dramatically affects toxicity properties. We
aim to assess the simultaneous binding effects of the two main chemotherapy drugs of 5 …
aim to assess the simultaneous binding effects of the two main chemotherapy drugs of 5 …
[HTML][HTML] Modeling the tumor microenvironment of ovarian cancer: the application of self-assembling biomaterials
AK Mendoza-Martinez, D Loessner, A Mata… - Cancers, 2021 - mdpi.com
Simple Summary The tumor-surrounding niche comprises not only cancer cells but also
stromal cells, signaling molecules, secreted factors and the extracellular matrix. This niche …
stromal cells, signaling molecules, secreted factors and the extracellular matrix. This niche …
[HTML][HTML] Numerical investigation of moving gel wall formation in a Y-shaped microchannel
Molecular diffusive membranes play crucial roles in the field of microfluidics for biological
applications eg, 3D cell culture and biosensors. Hydrogels provide a range of benefits such …
applications eg, 3D cell culture and biosensors. Hydrogels provide a range of benefits such …
[HTML][HTML] Functional precision oncology: the next frontier to improve glioblastoma outcome?
D Panovska, F De Smet - International journal of molecular sciences, 2022 - mdpi.com
Glioblastoma remains the most malignant and intrinsically resistant brain tumour in adults.
Despite intensive research over the past few decades, through which numerous potentially …
Despite intensive research over the past few decades, through which numerous potentially …
[HTML][HTML] Prebiotic chemistry experiments using microfluidic devices
KM Lerin-Morales, LF Olguín, E Mateo-Martí… - Life, 2022 - mdpi.com
Microfluidic devices are small tools mostly consisting of one or more channels, with
dimensions between one and hundreds of microns, where small volumes of fluids are …
dimensions between one and hundreds of microns, where small volumes of fluids are …
A modular, reversible sealing, and reusable microfluidic device for drug screening
FF Vit, R Nunes, YT Wu, MCP Soares, N Godoi… - Analytica chimica …, 2021 - Elsevier
Preclinical tests for evaluating potential drug candidates using conventional protocols can
be exhaustive and high-cost processes. Microfluidic technologies that can speed up this …
be exhaustive and high-cost processes. Microfluidic technologies that can speed up this …
Investigation of anti-cancer effects of new pyrazino [1, 2-a] benzimidazole derivatives on human glioblastoma cells through 2D in vitro model and 3D-printed …
Aims Recent studies show targeted therapy of new pyrazino [1, 2-a] benzimidazole
derivatives with COX-II inhibitory effects on different cancer cells. This study aimed to …
derivatives with COX-II inhibitory effects on different cancer cells. This study aimed to …
[HTML][HTML] Microfluidic Chip for Detection of Drug Resistance at the Single-Cell Level
K Song, Z Yu, X Zu, L Huang, D Fu, J Yao, Z Hu, Y Xue - Micromachines, 2022 - mdpi.com
Drug-resistant bacterial strains seriously threaten human health. Rapid screening of
antibiotics is urgently required to improve clinical treatment. Conventional methods of …
antibiotics is urgently required to improve clinical treatment. Conventional methods of …