Two-photon imaging (TPI) microscopy, namely, two-photon excited fluorescence (TPEF),
fluorescence lifetime imaging (FLIM), and second-harmonic generation (SHG) modalities …

Purpose: Although extrinsic fluorophores can be introduced to label specific cell types in the
retina, endogenous fluorophores, such as NAD (P) H, FAD, collagen, and others, are …

Outflow resistance in the aqueous drainage tract distal to trabecular meshwork is potentially
an important determinant of intraocular pressure and success of trabecular bypass …

Purpose: The purpose of this study was to evaluate the feasibility of using two-photon
imaging (TPI) to assess the condition of human corneas for transplantation. Methods …

Primary open angle glaucoma (POAG) is the most common type of glaucoma. At the
mechanistic level, POAG is thought to be caused by extracellular matrix (ECM) deposition in …

A nonlinear optical (NLO) microscopy system integrating stimulated Raman scattering
(SRS), two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) …

This work applies sparse representations and nonlinear image processing to two inverse
imaging problems. The first problem involves image restoration, where the aim is to …

The lamina cribrosa (LC) is a connective tissue in the posterior eye with a complex mesh-
like trabecular microstructure, through which all the retinal ganglion cell axons and central …

The development of technologies to characterize the ocular aqueous outflow system (AOS)
is important for the understanding of the pathophysiology of glaucoma. Multiphoton …

The purpose of this study is to provide an intravital noninvasive multiphoton microscopic
platform for long-term ocular imaging in transgenic fluorescent mice with subcellular …