Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases

Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Endocrine and paracrine characteristics of neuroendocrine prostate cancer

T Arman, PS Nelson - Frontiers in Endocrinology, 2022 - frontiersin.org
Prostate cancer is a common malignancy affecting men worldwide. While the vast majority of
newly diagnosed prostate cancers are categorized as adenocarcinomas, a spectrum of …

[HTML][HTML] Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory

X Yuan, JA Seneviratne, S Du, Y Xu, Y Chen, Q Jin… - Cell Reports, 2022 - cell.com
Peripheral neuroblastic tumors (PNTs) represent a spectrum of neural-crest-derived tumors,
including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Malignant cells in …

[HTML][HTML] RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation

K Zhu, T Gao, Z Wang, L Zhang, K Tan, Z Lv - Cell Death Discovery, 2023 - nature.com
Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-
methyladenosine (m6A) modification is closely related to multiple cancer pathological …

The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma

LM Parkinson, SL Gillen, LM Woods… - Frontiers in Cell and …, 2022 - frontiersin.org
Neuroblastoma is believed to arise from sympathetic neuroblast precursors that fail to
engage the neuronal differentiation programme, but instead become locked in a pro …

Development and validation of a CT‐based radiomics signature for identifying high‐risk neuroblastomas under the revised Children's Oncology Group classification …

H Wang, M Xie, X Chen, J Zhu, H Ding… - Pediatric Blood & …, 2023 - Wiley Online Library
Background To develop and validate a radiomics signature based on computed tomography
(CT) for identifying high‐risk neuroblastomas. Procedure This retrospective study included …

Epigenetic Dysregulation in MYCN-Amplified Neuroblastoma

S Epp, SM Chuah, M Halasz - International Journal of Molecular Sciences, 2023 - mdpi.com
Neuroblastoma (NB), a childhood cancer arising from the neural crest, poses significant
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …

Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines

TA Salamone, L Rutigliano, B Pennacchi… - Journal of Colloid and …, 2023 - Elsevier
Abstract Hypothesis Colloidal gold nanoparticles (AuNPs) functionalised with hydrophilic
thiols can be used as drug delivery probes, thanks to their small size and hydrophilic …

A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics

HM Lee, WC Wright, M Pan, J Low, D Currier… - Nature …, 2023 - nature.com
Combination chemotherapy is crucial for successfully treating cancer. However, the
enormous number of possible drug combinations means discovering safe and effective …

Dinutuximab beta combined with chemotherapy in patients with relapsed or refractory neuroblastoma

A Wieczorek, A Zaniewska-Tekieli, K Ehlert… - Frontiers in …, 2023 - frontiersin.org
Prognosis in children with refractory and relapsed high-risk neuroblastoma is poor. Only a
minority of patients obtain remission when treated with second-line chemotherapy regimens …