Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases
Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …
Endocrine and paracrine characteristics of neuroendocrine prostate cancer
T Arman, PS Nelson - Frontiers in Endocrinology, 2022 - frontiersin.org
Prostate cancer is a common malignancy affecting men worldwide. While the vast majority of
newly diagnosed prostate cancers are categorized as adenocarcinomas, a spectrum of …
newly diagnosed prostate cancers are categorized as adenocarcinomas, a spectrum of …
[HTML][HTML] Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory
X Yuan, JA Seneviratne, S Du, Y Xu, Y Chen, Q Jin… - Cell Reports, 2022 - cell.com
Peripheral neuroblastic tumors (PNTs) represent a spectrum of neural-crest-derived tumors,
including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Malignant cells in …
including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Malignant cells in …
[HTML][HTML] RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation
K Zhu, T Gao, Z Wang, L Zhang, K Tan, Z Lv - Cell Death Discovery, 2023 - nature.com
Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-
methyladenosine (m6A) modification is closely related to multiple cancer pathological …
methyladenosine (m6A) modification is closely related to multiple cancer pathological …
The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma
LM Parkinson, SL Gillen, LM Woods… - Frontiers in Cell and …, 2022 - frontiersin.org
Neuroblastoma is believed to arise from sympathetic neuroblast precursors that fail to
engage the neuronal differentiation programme, but instead become locked in a pro …
engage the neuronal differentiation programme, but instead become locked in a pro …
Development and validation of a CT‐based radiomics signature for identifying high‐risk neuroblastomas under the revised Children's Oncology Group classification …
H Wang, M Xie, X Chen, J Zhu, H Ding… - Pediatric Blood & …, 2023 - Wiley Online Library
Background To develop and validate a radiomics signature based on computed tomography
(CT) for identifying high‐risk neuroblastomas. Procedure This retrospective study included …
(CT) for identifying high‐risk neuroblastomas. Procedure This retrospective study included …
Epigenetic Dysregulation in MYCN-Amplified Neuroblastoma
S Epp, SM Chuah, M Halasz - International Journal of Molecular Sciences, 2023 - mdpi.com
Neuroblastoma (NB), a childhood cancer arising from the neural crest, poses significant
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …
Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines
TA Salamone, L Rutigliano, B Pennacchi… - Journal of Colloid and …, 2023 - Elsevier
Abstract Hypothesis Colloidal gold nanoparticles (AuNPs) functionalised with hydrophilic
thiols can be used as drug delivery probes, thanks to their small size and hydrophilic …
thiols can be used as drug delivery probes, thanks to their small size and hydrophilic …
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics
Combination chemotherapy is crucial for successfully treating cancer. However, the
enormous number of possible drug combinations means discovering safe and effective …
enormous number of possible drug combinations means discovering safe and effective …
Dinutuximab beta combined with chemotherapy in patients with relapsed or refractory neuroblastoma
A Wieczorek, A Zaniewska-Tekieli, K Ehlert… - Frontiers in …, 2023 - frontiersin.org
Prognosis in children with refractory and relapsed high-risk neuroblastoma is poor. Only a
minority of patients obtain remission when treated with second-line chemotherapy regimens …
minority of patients obtain remission when treated with second-line chemotherapy regimens …