Ki-67 has been widely used as an indicator of cell proliferation in gliomas. However, the role
of Ki-67 as a prognostic marker is still undefined. Thus, we conducted a meta-analysis of the …

The current WHO classification of human astrocytomas has limitations in predicting
prognosis and diagnosis, and there is a need for additional factors. Several studies have …

In current clinical practice, histology-based grading of diffuse infiltrative gliomas is the best
predictor of patient survival time. Yet histology provides little insight into the underlying …

The primary goal of this Phase I study was to assess the safety and bioactivity of tumor lysate-
pulsed dendritic cell (DC) vaccination to treat patients with glioblastoma multiforme and …

3′-Deoxy-3′-18F-fluorothymidine (18F-FLT) is a recently developed PET tracer to image
tumor cell proliferation. We characterized 18F-FLT PET of brain gliomas and compared 18F …

Purpose Hyperglycemia has been associated with poor outcomes in many disease states.
This retrospective study assessed the association between hyperglycemia and survival in …

Chemotherapy in glioma is poorly effective: the blood–brain barrier and intrinsic and/or
acquired drug resistance of tumor cells could partly explain this lack of major effect. We …

In order to compare in vivo metabolism between malignant gliomas and normal brain, 13C
magnetic resonance (MR) spectroscopic imaging data were acquired from rats with human …

Purpose: Although the development of immune-based therapies for various cancers
including malignant glioma has been heralded with much hope and optimism, objective …

Purpose To correlate and compare diagnostic performance with amide proton transfer (APT)
imaging as a tumor proliferation index with that with magnetic resonance (MR) spectroscopy …