Endocytosis, the process whereby the plasma membrane invaginates to form vesicles, is
essential for bringing many substances into the cell and for membrane turnover. The …

In cells the de novo nucleation of actin filaments from monomers requires actin-nucleating
proteins. These fall into three main families–the Arp2/3 complex and its nucleation …

Cancer cell-derived extracellular vesicles (EVs) are increasingly being recognized as
genuine invasive structures as they contribute to many aspects of invasion and metastasis …

Multiple mechanisms of senescence induction exist including telomere attrition, oxidative
stress, oncogene expression and DNA damage signalling. The regulation of the cellular …

Background Branched actin filament networks driving cell motility, endocytosis, and
intracellular transport are assembled in seconds by the Arp2/3 complex and must be equally …

Guard cell actin reorganization has been observed in stomatal responses to a wide array of
stimuli. However, how the guard cell signaling machinery regulates actin dynamics is poorly …

The Arp2/3 complex polymerizes new actin filaments from the sides of existing filaments,
forming Y-branched networks that are critical for actin-mediated force generation. Binding of …

Abstract Actin-related protein 2/3 complex (ARPC2) is an actin‑binding component involved
in the regulation of actin polymerization. It mediates the formation of branched actin …

Airway epithelial cells (AECs) participate in allergic airway inflammation by producing
mediators in response to allergen stimulation. Whether ovalbumin (OVA) challenge …

Gravitropism is vital for shaping directional plant growth in response to the forces of gravity.
Signals perceived in the gravity-sensing cells can be converted into biochemical signals and …