Non-coding RNAs and potential therapeutic targeting in cancer

S Toden, TJ Zumwalt, A Goel - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …

The origin and evolution of cell types

D Arendt, JM Musser, CVH Baker, A Bergman… - Nature Reviews …, 2016 - nature.com
Cell types are the basic building blocks of multicellular organisms and are extensively
diversified in animals. Despite recent advances in characterizing cell types, classification …

Portrait of the PI3K/AKT pathway in colorectal cancer

SA Danielsen, PW Eide, A Nesbakken, T Guren… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Abstract PI3K/AKT signaling leads to reduced apoptosis, stimulates cell growth and
increases proliferation. Under normal conditions, PI3K/AKT activation is tightly controlled …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

Increased brain-specific MiR-9 and MiR-124 in the serum exosomes of acute ischemic stroke patients

Q Ji, Y Ji, J Peng, X Zhou, X Chen, H Zhao, T Xu… - PloS one, 2016 - journals.plos.org
The aims of this study were to examine the alternation in serum exosome concentrations
and the levels of serum exosomal miR-9 and miR-124, two brain-specific miRNAs, in acute …

Non-coding RNAs in breast cancer: intracellular and intercellular communication

CM Klinge - Non-coding RNA, 2018 - mdpi.com
Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in
breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes …

N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1

H Wang, Q Deng, Z Lv, Y Ling, X Hou, Z Chen… - Molecular cancer, 2019 - Springer
Background Brain metastasis (BM) is one of the principal causes of mortality for lung cancer
patients. While the molecular events that govern BM of lung cancer remain frustrating …

MicroRNAs in cancer: from developmental genes in worms to their clinical application in patients

M Pichler, GA Calin - British journal of cancer, 2015 - nature.com
Several discoveries have paved the way to personalise cancer medicine and a tremendous
gain of knowledge in genomics and molecular mechanisms of cancer progression …

Staphylococcus aureus biofilm infection compromises wound healing by causing deficiencies in granulation tissue collagen

S Roy, S Santra, A Das, S Dixith, M Sinha… - Annals of …, 2020 - journals.lww.com
Objective: The objective of this work was to causatively link biofilm properties of bacterial
infection to specific pathogenic mechanisms in wound healing. Background: Staphylococcus …

Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals

S Tarallo, G Ferrero, F De Filippis, A Francavilla… - Gut, 2022 - gut.bmj.com
Objectives MicroRNA (miRNA) profiles have been evaluated in several biospecimens in
relation to common diseases for which diet may have a considerable impact. We aimed at …