General and central nervous system anatomy and physiology in children is different to that of
adults and this is relevant to traumatic brain injury (TBI) and spinal cord injury. The …

Developmental changes in children can affect the disposition and clinical effects of a drug,
indicating that scaling an adult dose simply down per linear weight can potentially lead to …

Production of energy for the maintenance of ionic disequilibria necessary for generation and
transmission of nerve impulses is one of the primary functions of the brain. This review …

Background Cerebral and cardiac blood flow are important to the pathophysiology and
development of cerebro‐and cardiovascular diseases. The purpose of this study was to …

Arterial spin labeling is a magnetic resonance method for the measurement of cerebral
blood flow. In its simplest form, the perfusion contrast in the images gathered by this …

To establish reference data and to investigate the development of haemodynamics in the
extracranial carotid and vertebral arteries, we performed a prospective study in 78 age-and …

Purpose To test the feasibility of pediatric perfusion imaging using a pulsed arterial spin
labeling (ASL) technique at 1.5 T. Materials and Methods ASL perfusion imaging was …

Background and Purpose—Global cerebral blood flow (CBF) is an important yet largely
unknown quantity in the treatment of neurological intensive care patients. Color duplex …

Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

Background and Purpose—Vertebrobasilar ischemia has been attributed to a reduction of
net vertebral artery flow volume, the product of mean flow velocity and the cross-sectional …