Dose-rate effects and the repair of radiation damage

GG Steel, JD Down, JH Peacock… - Radiotherapy and …, 1986 - Elsevier
The extent of dose-sparing that occurs in a variety of cell lines and in vivo cell systems as a
results of a reduction in dose-rate is reviewed. The emphasis is on the range from around …

Idiopathic pneumonia syndrome after bone marrow transplantation: the role of pre‐transplant radiation conditioning and local cytokine dysregulation in promoting lung …

G Shankar, DA Cohen - International journal of experimental …, 2001 - Wiley Online Library
Pulmonary complications and graft‐vs.‐host disease (GVHD) remain severe threats to
survival after bone marrow transplantation (BMT). Idiopathic pneumonia syndrome (IPS) …

Effect of dose-rate on total body irradiation: lethality and pathologic findings

EL Travis, LJ Peters, J McNeill, HD Thames Jr… - Radiotherapy and …, 1985 - Elsevier
The effect of low dose-rate total body irradiation (TBI) on hemopoietic and nonhemopoietic
lethality has been studied in BALB/c mice using dose-rates ranging from 25 to 1 cGy/min …

Radiation effects on the respiratory system

RP Hill - The British Journal of Radiology, 2005 - academic.oup.com
This paper discusses the lung response to irradiation in the context of accidental radiation
exposure. The lung is a relatively radiation sensitive organ with a response to irradiation that …

Fractionation and dose rate effects in mice: a model for bone marrow transplantation in man

NJ Tarbell, DA Amato, JD Down, P Mauch… - International Journal of …, 1987 - Elsevier
This study was designed to compare several fractionation and dose rate schedules to
optimize the therapeutic ratio for total body irradiation (TBI). C3H/HeJ mice were given TBI …

Repair in the mouse lung during low dose-rate irradiation

JD Down, DF Easton, GG Steel - Radiotherapy and Oncology, 1986 - Elsevier
The thorax of CBA mice was exposed to 60 Co γ-rays at dose rates ranging from 100 to 2
cGy/min. Iso-effectdoses (ED 50) were calculated for early and late lung damage from dose …

Post-irradiation lung density changes measured by computerized tomography

J Van Dyk, RP Hill - International Journal of Radiation Oncology* Biology …, 1983 - Elsevier
To investigate the possibility of using computerized tomography (CT) as a prognostic
indicator of radiation induced lung toxicity, a series of CT scans were performed on one …

Lung damage following bone marrow transplantation: I. The contribution of irradiation

BL Cardozo, H Zoetelief, DW van Bekkum… - International Journal of …, 1985 - Elsevier
High dose whole body irradiation is commonly included in conditioning regimens for bone
marrow transplantation for treatment of patients with hematological malignancies. Interstitial …

Radiobiological aspects of continuous low dose-rate irradiation and fractionated high dose-rate irradiation

I Turesson - Radiotherapy and Oncology, 1990 - Elsevier
The biological effects of continuous low dose-rate irradiation and fractionated high dose-rate
irradiation in interstitial and intracavitary radiotherapy and total body irradiation are …

Derivation and application of equations describing the effects of fractionated protracted irradiation, based on multiple and incomplete repair processes. Part 2 …

WT Millar, PA Canney - International journal of radiation biology, 1993 - Taylor & Francis
General equations for fractionated protracted irradiation have been applied to the analysis of
mouse lung data derived from isoeffect protocols. The data were accrued from a spectrum of …