In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

The success of pregnancy relies on the fine adjustment of the maternal immune system to
tolerate the allogeneic fetus. Trophoblasts carrying paternal antigens are the only fetal …

Microglia activation, increased IL-6 and decreased TGF-β were found in depressed patients
or in animal models of depression. IL-6 enhances T helper 17 cell differentiation, thereby …

Pregnancy is a state of immunological balance during which the mother and the developing
fetus must tolerate each other while maintaining sufficient immunocompetence to ward off …

Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

Background Several studies report the role of Regulatory T-cells (Tregs) in the
pathophysiology of pregnancy adverse outcomes. Objective The aim of this systematic …

The placenta is a transient organ that forms during pregnancy and acts as a biological
barrier, mediating exchange between maternal and fetal circulation. Placental disorders …

Inflammation is generally thought to be involved in the occurrence and development of
preeclampsia (PE), but its specific effect on PE remains unclear. In the present study, the …

Preeclampsia (PE) is a leading cause of maternal and fetal mortality worldwide. The immune
system plays a critical role in normal pregnancy progression; however, inappropriate …

ABSTRACT T-regulatory (Treg)/T-helper 17 (Th17) imbalance is associated with
preeclampsia (PE). Herein, we aimed to explore the effect and mechanism of lncRNA …