The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

[HTML][HTML] Additive manufacturing of sustainable biomaterials for biomedical applications

ZU Arif, MY Khalid, R Noroozi, M Hossain… - Asian Journal of …, 2023 - Elsevier
Biopolymers are promising environmentally benign materials applicable in multifarious
applications. They are especially favorable in implantable biomedical devices thanks to their …

Poly (lactic acid)-based microparticles for drug delivery applications: An overview of recent advances

A Vlachopoulos, G Karlioti, E Balla, V Daniilidis… - Pharmaceutics, 2022 - mdpi.com
The sustained release of pharmaceutical substances remains the most convenient way of
drug delivery. Hence, a great variety of reports can be traced in the open literature …

Comparative statistical analysis of the release kinetics models for nanoprecipitated drug delivery systems based on poly (lactic-co-glycolic acid)

NS Heredia, K Vizuete, M Flores-Calero, K Pazmiño V… - PLoS …, 2022 - journals.plos.org
Poly (lactic-co-glycolic acid) is one of the most used polymers for drug delivery systems
(DDSs). It shows excellent biocompatibility, biodegradability, and allows spatio-temporal …

[HTML][HTML] Recent advances in long-acting drug delivery systems for anticancer drug

C Pacheco, A Baiao, T Ding, W Cui… - Advanced Drug Delivery …, 2023 - Elsevier
The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

PLGA/PLA-based long-acting injectable depot microspheres in clinical use: production and characterization overview for protein/peptide delivery

A Butreddy, RP Gaddam, N Kommineni… - International journal of …, 2021 - mdpi.com
Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …

New insights into water-in-oil-in-water (W/O/W) double emulsions: Properties, fabrication, instability mechanism, and food applications

A Kumar, R Kaur, V Kumar, S Kumar, R Gehlot… - Trends in Food Science …, 2022 - Elsevier
Background Nowadays people demand for healthy, convenient, and wholesome foods.
Double emulsions have attracted widespread attention in the food industry owing to their …

Recent advancements in microneedle technology for multifaceted biomedical applications

D Kulkarni, F Damiri, S Rojekar, M Zehravi… - Pharmaceutics, 2022 - mdpi.com
Microneedle (MNs) technology is a recent advancement in biomedical science across the
globe. The current limitations of drug delivery, like poor absorption, low bioavailability …

Self-assembling peptides: From design to biomedical applications

S La Manna, C Di Natale, V Onesto… - International journal of …, 2021 - mdpi.com
Self-assembling peptides could be considered a novel class of agents able to harvest an
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …