HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

Cerebrospinal fluid metabolomics: Detection of neuroinflammation in human central nervous system disease

J Yan, U Kuzhiumparambil… - Clinical & …, 2021 - Wiley Online Library
The high morbidity and mortality of neuroinflammatory diseases drives significant interest in
understanding the underlying mechanisms involved in the innate and adaptive immune …

Mogamulizumab (Anti-CCR4) in HTLV-1–associated myelopathy

T Sato, ALG Coler-Reilly, N Yagishita… - … England Journal of …, 2018 - Mass Medical Soc
Background Human T-lymphotropic virus type 1 (HTLV-1) causes the debilitating
neuroinflammatory disease HTLV-1–associated myelopathy–tropical spastic paraparesis …

[HTML][HTML] 40 years of the human T-cell leukemia virus: past, present, and future

Y Tagaya, M Matsuoka, R Gallo - F1000Research, 2019 - ncbi.nlm.nih.gov
It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

Inflammatory manifestations of HTLV-1 and their therapeutic options

F Martin, GP Taylor, S Jacobson - Expert review of clinical …, 2014 - Taylor & Francis
Human T lymphotropic virus type 1 (HTLV-1) is one of the most intriguing retroviruses
infecting humans. Most commonly, infection remains undetected, since it does not cause …

[HTML][HTML] Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

[HTML][HTML] An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory …

J Yamauchi, N Araya, N Yagishita, T Sato… - Pharmacology & …, 2021 - Elsevier
Human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a rare inflammatory disease causing unremitting and progressive …

[HTML][HTML] HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

N Araya, T Sato, H Ando, U Tomaru… - The Journal of …, 2014 - Am Soc Clin Investig
Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

[HTML][HTML] Proposal of classification criteria for HTLV-1-associated myelopathy/tropical spastic paraparesis disease activity

T Sato, N Yagishita, K Tamaki, E Inoue… - Frontiers in …, 2018 - frontiersin.org
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. While the disease …

[HTML][HTML] Efficacy of corticosteroid therapy for HTLV-1-associated myelopathy: a randomized controlled trial (HAMLET-P)

J Yamauchi, K Tanabe, T Sato, M Nakagawa… - Viruses, 2022 - mdpi.com
Corticosteroids are most commonly used to treat HTLV-1-associated myelopathy (HAM);
however, their clinical efficacy has not been tested in randomized clinical trials. This …