Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years
in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that …

Abstract Background Radix Bupleuri (RB) has been widely used in Chinese Traditional
Medicine for over 2000 years and is currently marketed in China as Chai-Hu-Shu-Gan …

Covering: up to May 2010 This review (with 335 references cited) is devoted to pentacyclic
triterpenes. The total synthesis, semi-synthesis, structural modification, and metabolic …

Abstract Objectives Radix Bupleuri represents one of the most successful and widely used
herbal drugs in Asia for treatment of many diseases over the past 2000 years. Thorough …

Background & Aims A vaccine against hepatitis C virus (HCV) is unavailable and cost-
effective antivirals that prevent HCV infection and re-infection, such as in the transplant …

Curcumin and saikosaponin A as antioxidants improve antioxidant status. This study
investigated the anti-inflammatory and antifibrotic actions of curcumin and saikosaponin A …

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-
inflammatory effects. The purpose of this study was to explore the mechanism underlying …

Over the past decades, a number of phytochemicals have been reported to possess potent
pharmacological effects. Saikosaponins represent a group of oleanane derivatives, usually …

NLRP3 inflammasome activation results in severe liver inflammation and injury.
Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study …

Chronic pancreatitis is characterized by pancreatic fibrosis, associated with excessive
activation of pancreatic stellate cells (PSCs) and increased expression of transforming …