Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology
F Yang, X Dong, X Yin, W Wang… - BioMed Research …, 2017 - Wiley Online Library
Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years
in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that …
in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that …
A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins
X Li, X Li, N Huang, R Liu, R Sun - Phytomedicine, 2018 - Elsevier
Abstract Background Radix Bupleuri (RB) has been widely used in Chinese Traditional
Medicine for over 2000 years and is currently marketed in China as Chai-Hu-Shu-Gan …
Medicine for over 2000 years and is currently marketed in China as Chai-Hu-Shu-Gan …
Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases
H Sheng, H Sun - Natural product reports, 2011 - pubs.rsc.org
Covering: up to May 2010 This review (with 335 references cited) is devoted to pentacyclic
triterpenes. The total synthesis, semi-synthesis, structural modification, and metabolic …
triterpenes. The total synthesis, semi-synthesis, structural modification, and metabolic …
Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of action
Abstract Objectives Radix Bupleuri represents one of the most successful and widely used
herbal drugs in Asia for treatment of many diseases over the past 2000 years. Thorough …
herbal drugs in Asia for treatment of many diseases over the past 2000 years. Thorough …
Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry
Background & Aims A vaccine against hepatitis C virus (HCV) is unavailable and cost-
effective antivirals that prevent HCV infection and re-infection, such as in the transplant …
effective antivirals that prevent HCV infection and re-infection, such as in the transplant …
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats
SJ Wu, KW Tam, YH Tsai, CC Chang… - The American journal of …, 2010 - World Scientific
Curcumin and saikosaponin A as antioxidants improve antioxidant status. This study
investigated the anti-inflammatory and antifibrotic actions of curcumin and saikosaponin A …
investigated the anti-inflammatory and antifibrotic actions of curcumin and saikosaponin A …
[HTML][HTML] Saikosaponin d alleviates liver fibrosis by negatively regulating the ROS/NLRP3 inflammasome through activating the ERβ pathway
K Zhang, L Lin, Y Zhu, N Zhang, M Zhou… - Frontiers in …, 2022 - frontiersin.org
Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-
inflammatory effects. The purpose of this study was to explore the mechanism underlying …
inflammatory effects. The purpose of this study was to explore the mechanism underlying …
Saikosaponins: a review of pharmacological effects
XQ Li, YN Song, SJ Wang, K Rahman… - Journal of Asian …, 2018 - Taylor & Francis
Over the past decades, a number of phytochemicals have been reported to possess potent
pharmacological effects. Saikosaponins represent a group of oleanane derivatives, usually …
pharmacological effects. Saikosaponins represent a group of oleanane derivatives, usually …
Inhibition of oxidative stress and NLRP3 inflammasome by Saikosaponin-d alleviates acute liver injury in carbon tetrachloride-induced hepatitis in mice
Y Chen, R Que, L Lin, Y Shen… - International Journal of …, 2020 - journals.sagepub.com
NLRP3 inflammasome activation results in severe liver inflammation and injury.
Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study …
Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study …
Saikosaponin d ameliorates pancreatic fibrosis by inhibiting autophagy of pancreatic stellate cells via PI3K/Akt/mTOR pathway
LH Cui, CX Li, YZ Zhuo, L Yang, NQ Cui… - Chemico-biological …, 2019 - Elsevier
Chronic pancreatitis is characterized by pancreatic fibrosis, associated with excessive
activation of pancreatic stellate cells (PSCs) and increased expression of transforming …
activation of pancreatic stellate cells (PSCs) and increased expression of transforming …