Beyond Mortality: Exploring the Influence of Plant Phenolics on Modulating Ferroptosis—A Systematic Review

N Živanović, M Lesjak, N Simin, SKS Srai - Antioxidants, 2024 - mdpi.com
Ferroptosis is a recently discovered type of programmed cell death that is mechanistically
different from other types of programmed cell death such as apoptosis, necroptosis, and …

The Interplay between Ferroptosis and Neuroinflammation in Central Neurological Disorders

Y Xu, B Jia, J Li, Q Li, C Luo - Antioxidants, 2024 - mdpi.com
Central neurological disorders are significant contributors to morbidity, mortality, and long-
term disability globally in modern society. These encompass neurodegenerative diseases …

miR-15b-5p promotes HgCl2-induced chicken embryo kidney cells ferroptosis by targeting β-TrCP-mediated ATF4 ubiquitin degradation

HY Fu, Y Li, H Cui, JZ Li, WX Xu, X Wang, RF Fan - Toxicology, 2024 - Elsevier
Abstract Mercuric chloride (HgCl 2), a widespread environmental pollutant, induces
ferroptosis in chicken embryonic kidney (CEK) cells. Whereas activating transcription factor …

[HTML][HTML] Prognostic Values of Ferroptosis-Related Proteins ACSL4, SLC7A11, and CHAC1 in Cholangiocarcinoma

S Amontailak, A Titapun, A Jusakul, R Thanan… - Biomedicines, 2024 - mdpi.com
Background: The epithelial malignant tumor known as cholangiocarcinoma (CCA) is most
commonly found in Southeast Asia, particularly in northeastern Thailand. Previous research …

FNDC5/irisin ameliorates bone loss of type 1 diabetes by suppressing endoplasmic reticulum stress‑mediated ferroptosis

Q Dong, Z Han, M Gao, L Tian - Journal of Orthopaedic Surgery and …, 2024 - Springer
Background Ferroptosis is known to play a crucial role in diabetic osteopathy. However, key
genes and molecular mechanisms remain largely unclear. This study aimed to identify a …

The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target

M Wang, J Zhao, J Chen, T Long, M Xu, T Luo, Q Che… - PeerJ, 2024 - peerj.com
Liver disease is a common and serious threat to human health. The progression of liver
diseases is influenced by many physiologic processes, including oxidative stress …

Extraction and purification, pharmacological action, synthesis and product development of salidroside: a review

Y Liu, L Dan, J Tang, Z Yin, L Yang, D Zhang… - Medicinal Chemistry …, 2024 - Springer
Salidroside (Sal), a natural phenolic glycoside ubiquitous across all species of the Rhodiola
genus, has garnered considerable attention in contemporary pharmacological research. Its …

Endoplasmic Reticulum Stress Promotes Neuronal Damage in Neonatal Hypoxic-Ischemic Brain Damage by Inducing Ferroptosis

Y Ji, H Liu, F Niu, B Kang, X Luo, H Yang, Z Tian… - Molecular …, 2024 - Springer
Hypoxic-ischemic brain damage (HIBD) poses a significant risk of neurological damage in
newborns. This study investigates the impact of endoplasmic reticulum stress (ERS) on …

[HTML][HTML] Crosstalk between Endoplasmic Reticulum Stress and Ferroptosis in Liver Diseases

M Huang, Y Wang, X Wu, W Li - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
The endoplasmic reticulum (ER) played an important role in the folding, assembly and post-
translational modification of proteins. ER homeostasis could be disrupted by the …

Chac1 silencing mitigates hemorrhagic shock-induced intestinal injury by inhibiting oxidative stress and ferroptosis.

H Yao, Y Wang, W Zhou, C Xu, X Ge, J Zhu - Signa Vitae, 2023 - search.ebscohost.com
Hemorrhagic shock (HS) is a common and significant cause of mortality and morbidity, often
resulting in structural damage and dysfunction of the intestines. ChaC glutathionespecific …