Background: Prescriptions of off-label under-and overdosing of direct oral anticoagulants
(DOACs) are common for patients with atrial fibrillation, but their efficacy and safety remain …

Background: Several studies have investigated the role of off-label non-vitamin K antagonist
oral anticoagulants (NOACs) in patients with atrial fibrillation (AF). We aimed to compare the …

Background Although several meta‐analyses have examined the effects of off‐label
underdosing of nonvitamin K antagonist oral anticoagulants (NOACs) compared with their …

Background: The efficacy and safety profiles of nonrecommended direct oral anticoagulant
(DOAC) doses in patients with nonvalvular atrial fibrillation (NVAF) are still undefined …

Purpose To compare the effectiveness and safety of reduced or standard daily doses of
direct oral anticoagulants (DOACs) with warfarin in Japanese patients with nonvalvular atrial …

Background: Apixaban is commonly used to prevent stroke in older adults with nonvalvular
atrial fibrillation (AF). Although its package insert has specific dose reduction criteria …

Methods PubMed, Embase, Cochrane library, and ClinicalTrials. gov were searched from
2010 to July 5, 2024, for randomised controlled trials or observational studies that compared …

Introduction Off-label, under-, and overdosed direct oral anticoagulants (DOACs) are
commonly prescribed to patients with atrial fibrillation (AF), but real-world evidence on their …

Objetivo: Analisar e revisar a eficácia dos Novos Anticoagulantes Orais (NACOs) na
Fibrilação Atrial. Métodos: Revisão integrativa da literatura realizada a partir da pesquisa na …