The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and …

J Marín-Prida, A Rodríguez-Ulloa, V Besada… - Frontiers in …, 2023 - frontiersin.org
Introduction The antinociceptive and pharmacological activities of C-Phycocyanin (C-PC)
and Phycocyanobilin (PCB) in the context of inflammatory arthritis remain unexplored so far …

Pro-apoptotic and anti-inflammatory effects of araloside A on human rheumatoid arthritis fibroblast-like synoviocytes

Y Ding, Q Zhao, L Wang - Chemico-biological interactions, 2019 - Elsevier
Rheumatoid arthritis fibroblast-like synoviocytes play an essential role in the occurrence and
progression of rheumatoid arthritis. As the main pharmacologically active components of …

Deregulation of exosomal miRNAs in rheumatoid arthritis patients

MZ Hussain, MS Haris, M Rizwan, NS Ashraf… - Plos one, 2023 - journals.plos.org
Exosomes are small-diameter endosomal vesicles secreted in all biological fluids and play
biological/pathological roles in the cell. These pathological roles are played by exosome's …

4-Methylumbelliferone diminishes catabolically activated articular chondrocytes and cartilage explants via a mechanism independent of hyaluronan inhibition

S Ishizuka, EB Askew, N Ishizuka, CB Knudson… - Journal of Biological …, 2016 - ASBMB
Depletion of the cartilage proteoglycan aggrecan is one of the earliest events that occurs in
association with osteoarthritis. This loss is often accompanied by a coordinate loss in …

MiR-92a inhibits fibroblast-like synoviocyte proliferation and migration in rheumatoid arthritis by targeting AKT2

FY Yu, CQ Xie, C Jiang, JT Sun, HC Feng, C Li… - Journal of …, 2018 - Springer
Growing data have indicated that the miR-17–92 cluster is implicated in inflammatory
response and rheumatoid arthritis (RA). This study was aimed to investigate the effects of …

PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro

Y Yao, H Yu, Y Liu, Q Xu, X Li, X Meng… - Frontiers in …, 2018 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and its
pathogenesis remains unclear. Fibroblast-like synoviocytes (FLSs) play an important role in …

Recent findings regarding the effects of microRNAs on fibroblast-like synovial cells in rheumatoid arthritis

N Iwamoto, A Kawakami - Immunological medicine, 2019 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction characterized by marked hyperplasia of the lining layer of the synovium …

Withaferin A Alleviates Inflammation in Animal Models of Arthritis by Inhibiting the NF-κB Pathway and Cytokine Release

F Alenazi, S Moursi, M Mahmoud, SMA Shahid… - Chemico-Biological …, 2024 - Elsevier
Withaferin A, a steroid lactone from Withania somnifera, exhibits anti-inflammatory,
immunomodulatory, and antioxidant properties. This study investigated the effects of …

Lower Expression of miR-10a in Coronary Artery Disease and its Association with Pro/Anti-Inflammatory Cytokines.

N Moradi, R Ahmadi, S Fallah, R Fadaei… - Clinical …, 2018 - search.ebscohost.com
Background: Coronary artery disease (CAD) is the leading cause of death worldwide.
Atherosclerosis, the main underlying cause of CAD, is a progressive inflammatory disease …

Circulating Small Noncoding RNA Profiling as a Potential Biomarker of Atherosclerotic Plaque Composition in Type 1 Diabetes

A Giannella, E Castelblanco, CF Zambon… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Cardiovascular disease (CVD) accounts for most deaths in patients with type 1
diabetes (T1D); however, the determinants of plaque composition are unknown. miRNAs …