Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor
positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed …

Estrogen receptor-positive (ER+) is the most common subtype of breast cancer. Endocrine
therapy is the fundamental treatment against this entity, by directly or indirectly modifying …

Antiestrogens include agents such as tamoxifen, toremifene, raloxifene, and fulvestrant.
Currently, tamoxifen is the only drug approved for use in breast cancer chemoprevention …

As early as the 1800s, the actions of estrogen have been implicated in the development and
progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s …

A relatively small number of cells in the normal human mammary gland express receptors
for oestrogen and progesterone (ER and PR), and there is almost complete dissociation …

Purpose The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in
breast cancers has been intensely studied; however, there is still no real consensus …

Estrogen receptor (ER) has a crucial role in normal breast development and is expressed in
the most common breast cancer subtypes. Importantly, its expression is very highly …

In this study, an estrogen receptor (ER) α-expressing T47D cell line containing an inducible
tet-off FLAG-ERβ was used to examine the influence of ERβ on ERα activity. Real-time PCR …

Gliomas are the most common type of primary malignant brain tumor and have a very poor
prognosis. Little is known, however, about the etiology of these tumors. Evidence from a …

Recent work elucidating the role that the estrogen receptor β (ERβ), a member of the nuclear
receptor superfamily, plays in regulating various physiological functions has highlighted the …